Yongxing Zhou, MD| Neurology | MedStar Health

Yongxing Zhou, MD
Provider is directly employed by MedStar Health

4.6 out of 5 (260 reviews)

Specialities: Neurology

Languages: English


About me

Dr. Yongxing Zhou (pronounced “Joe”) cares for patients with a wide range of neurological needs and his subspecialty is epilepsy. Dr. Zhou is board-certified and completed his medical residency and internship at Florida State University, the University of Florida, and Howard University Hospital. Following those programs, Dr. Zhou conducted his fellowship training in epilepsy at George Washington University Hospital. He joined the medical staff at MedStar St. Mary’s Hospital in 2018.
Dr. Zhou specializes in neurology and epilepsy disorders and believes in treating the patient as a whole person. He gives each patient his focused attention, listens to their concerns, and takes the time to understand their symptoms to ensure the correct diagnosis. He partners with his patients to find the best treatment options for them, using evidence-based medicine and the latest advancements in the field. Dr. Zhou is committed to providing the best possible care and establishing long-lasting relationships with his patients.

Clinical areas of focus

  • Concussion
  • Encephalopathies
  • Facial Nerve Palsy And Paresis
  • Headache
  • Myasthenia Gravis
  • Neuropathy
  • Numbness
  • Tingling
  • Tremor
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Conditions and procedures

Conditions I treat

  • Abnormal Reflexes
  • Acute Inflammatory Demyelinating Polyneuropathy
  • Amyotrophic Lateral Sclerosis
  • Arm Weakness
  • Autoimmune Encephalitis
  • Benign Focal Amyotrophy
  • Benson's Syndrome
  • Bethlem Myopathy
  • Brachial Plexus Injury
  • Brain Arteriovenous Malformation (AVM)
  • Brain Injury
  • Brain Lesions
  • Cadasil
  • Cadasil Syndrome
  • Cancer Related Cognitive Disorder
  • Cerebral Aneurysm
  • Cerebral Microvascular Injury
  • Cerebral Small Vessel Disease (CSVD)
  • Cervical Spine Stress Fracture
  • Charcot Marie Tooth Disease
  • Chorea
  • Chronic Post Traumatic Headache
  • Concussion
  • Cranial Nerve Injury
  • Dejerine Sottas Disease
  • Diabetic Lumbosacral Radiculoplexus Neuropathy
  • Diabetic Neuropathy
  • Diplopia
  • Distal Motor Neuropathy
  • Distal Muscular Dystrophy
  • Distal Myopathy
  • Dropped Head Syndrome
  • Dural Arteriovenous Fistula
  • Dysarthria
  • Dysesthesia
  • Early Onset Dementia
  • Elevated Growth Hormone
  • Encephalitis
  • Encephalopathies
  • Episodic Migraine
  • Extrapyramidal Disorders
  • Eyelid Closure Weakness
  • Facial Droop
  • Facial Nerve Palsy
  • Facial Nerve Palsy And Paresis
  • Facial Nerve Paralysis
  • Facial Pain
  • Facioscapulohumeral Muscular Dystrophy
  • Femoral Neuropathy
  • Grand Mal Status Epilepticus
  • Guillain Barre Syndrome (GBS)
  • Hashimoto Encephalitis
  • Hashimoto Encephalopathy
  • Headache
  • HIV Myopathy
  • Hiv/Aids
  • Horner Syndrome
  • Inclusion Body Myopathy
  • Increased Intracranial Pressure
  • Intracranial Hypertension
  • Leg Numbness
  • Leg Weakness
  • Lip Droop
  • Lobar Atrophy Of Brain
  • Locked In Syndrome
  • Maternal Neurologic Disorders
  • Merosin Deficient Congenital Muscular Dystrophy
  • Metabolic Brain Disorders
  • Monomelic Amyotrophy
  • Moyamoya
  • Multifocal Acquired Demyelinating Sensorimotor Neuropathy
  • Multifocal Motor Neuropathy
  • Muscle Atrophy
  • Muscle Weakness
  • Myasthenia Gravis
  • Myelitis/Myelopathy
  • Myelopathy
  • Nerve Root Disorder
  • Neuralgia
  • Neuro Infectious Diseases
  • Neurocognitive Disorder
  • Neurodegenerative Diseases
  • Neuroinflammatory Disorders
  • Neurolysis
  • Neuroma
  • Neuromuscular Diseases
  • Neuropathy
  • Neurosyphilis
  • Neurovascular Disease
  • New Onset Refractory Status Epilepticus (NORSE)
  • Non Epileptic Event
  • Numbness
  • Occipital Neuralgia
  • Opsoclonus Myoclonus Ataxia Syndrome
  • Papilledema
  • Paramyotonia Congenita
  • Paresthesia
  • Parkinson's Disease (PD) Related Depression/Anxiety
  • Periodic Paralysis
  • Peripheral Nerve Disease
  • Peripheral Nerve Injury
  • Peripheral Neuropathy
  • Peroneal Nerve Injury
  • Pituitary Cancer
  • Plantar Nerve Lesions
  • Plexopathy
  • Radiculopathy
  • Receptive Aphasia
  • Semantic Dementia
  • Sensory Impairment
  • Sensory Neuronopathy
  • Sensory Problem
  • Slurred Speech
  • Small Fiber Neuropathy
  • Spasticity
  • Spinal Schwannoma
  • Spine Arteriovenous Malformation (AVM)
  • Sports Related Concussion
  • Sports Related Head Injury
  • Sports Related Spinal Cord Injury
  • Statin Myopathy
  • Stroke Related Spasticity
  • Tibial Neuropathy
  • Tingling
  • Tremor
  • Trigeminal Autonomic Cephalgias
  • Trigeminal Neuropathy
  • Trochlear Nerve Injury
  • Unable To Grip
  • Unsteady Gait
  • Vocal Tremor
  • Weakness
  • White Matter Hyperintensities
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Procedures I perform

  • Artificial Disc Replacement Surgery In The Cervical Spine
  • Artificial Disc Replacement Surgery In The Thoracic Spine
  • Calcitonin Gene Related Peptide (CGRP) Inhibitor
  • Capacity Assessment
  • Carbidopa Levodopa Intestinal Gel Therapy
  • Carbidopa Levodopa Oral Therapy
  • Dietary Management In Epilepsy
  • Electrodiagnostic Medicine
  • Electromyography
  • Epidural Injection
  • Epilepsy Medication Management
  • Evaluation For Deep Brain Stimulation (DBS)
  • Lumbar Spine Epidural Steroid Injection
  • Mri Guided Focused Ultrasound
  • Neuravive
  • Sports Related Concussion Testing
  • Thoracic Spine Epidural Steroid Injection
  • Vestibular Evoked Myogenic Potential (VEMP) Testing
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Practice locations

Distance from Change LocationEnter your Location

25500 Point Lookout Road
Floor 2
Leonardtown, MD, 20650


Fax 240-434-4022

Get Directions

miles away

Fax 240-434-4022


MedStar Medical Group accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Medical Group, please call your insurance company.

  • List of insurance plans we accept
    • Aetna Elect Choice/ EPO (Aetna Health Fund) Innovation Health: Network Only Plus
    • Aetna Quality Point of Service (POS)
    • Aetna USAccess (POS)
    • Aetna Student Health Insurance
    • Aetna Medicare Advantage HMO & PPO Plans
    • CFBCBS BlueChoice HMO
    • CFBCBS Blue Choice Opt Out Plus Open Access (POS)
    • CFBCBS Maryland Point of Service Plan (MPOS)
    • CFBCBS Federal Employee Program (Std. & Basic PPO)
    • CFBCBS Maryland Indemnity or PPO
    • CFBCBS (NCA) Indemnity
    • CIGNA HMO & Network (HMO)
    • CIGNA POS/Network POS
    • Great-West Healthcare POS/CIGNA
    • CIGNA Indemnity
    • Coventry Health Care of Virginia
    • Coventry of Delaware HMO/PPO
    • First Health PPO
    • Tricare Prime
    • Tricare Standard
    • Tricare Extra (Indemnity)
    • Tricare for Life (Medicare Supplemental Plan)
    • MedStar Family Choice - Maryland Health Choice
    • MedStar Select (MedStar Associates' Plan)
    • MedStar Medicare Choice
    • United Healthcare Select HMO - EPO/NPP
    • United Healthcare Select Plus (POS)
    • United Healthcare Choice Plus
    • United Student Resources
    • M.D. IPA (HMO)
    • M.D. IPA Preferred (POS)
    • Optimum Choice Preferred (POS) & OCI Direct (HMO)
    • Mamsi Life & Health (Indem./PPO)
    • Aetna Worker's Compensation Network
    • Coventry Health Care National Network PPO
    • Private Health Care Systems (PHCS) (PPO)
    • United Healthcare Options (PPO) (includes Empire PPO, GEHA, Compass Rose)
    • OneNet PPO, Inc.
    • United Healthcare Choice
    • United Healthcare Core Essential (HMO)
    • Optimum Choice
    • United Healthcare Navigate
    • United Healthcare Compass (HMO)
    • CIGNA HMO Open Access (OA)
    • Network OA
    • POS OA & OA Plus
    • PPO and PPO Plus
    • Choice Fund PPO
    • CFBSBC Blue Preferred PPO
    • HealthyBlue PPO
    • CFBCBS Blue Choice Opt Out Open Access
    • BlueChoice Open Access
    • Blue Choice Advantage & Healthy Blue (HMO, POS)
    • Aetna Traditional Choice (PPO)
    • Innovation Health: Indemnity
    • Aetna Open Choice (PPO)
    • Innovation Health: PPO
    • Aetna Managed Choice (POS)
    • Innovation Health: POS Plus
    • Aetna Elect Choice/ Open Access (POS)
    • Innovation Health: Open Network Only Plus
    • Aetna HMO-Open Access/Select OA/HealthFund/Health Network Option OA
    • Innovation Health: POS
    • Open HMO
    • Opoen HMO Option
    • Open EPO Plus
    • Aetna Managed Choice Open Access (POS)
    • Choice POS & Choice POS II
    • Innovation Health: Open POS Plus
    • Open POS II
    • Aetna HMO
    • Select HMO/HealthFund/Health Network
    • Aetna Innovations: HMO & EPO Plus


Board Certification: American Board of Psychiatry and Neurology, Neurology

Fellowship Program: George Washington University Hospital (2018)

Residency Program: Howard University Hospital (2017)

Residency Program: Shands Hospital at the University of Florida (2014)

Internship Program: Tallahassee Memorial Regional Medical Center (2013)

Medical School: Central South University (1987)


  • 2000    The sixth annual NIH-wide Fellows Award for Research Excellence (FARE), Department of Public Health, NIH, USA 2015    NIH/NMA Fellow Award, USA 2016    AAN resident scholarship, USA 

News and publications

1. Igarashi S, Takiyama Y, Cancel G, Rogaeva EA, Sasaki H, Wakisaka A, Zhou YX, Takano H, Endo K, Sanpei K, Oyake M, Tanaka H, Stevanin G, Abbas N, Durr A, Rogaev EI, Sherrington R, Tsuda T, Ikeda M, Cassa E, Nishizawa M, Benomar A, Julien J, Weissenbach J, Tsuji S. Intergenerational instability of the CAG repeat of the gene for Machado-Joseph disease (MJD1) is affected by the genotype of the normal chromosome: implications for the molecular mechanisms of the instability of the CAG repeat. Human Molecular Genetics 1996; 5:923-932. 

2. Zhou YX, Takiyama Y, Igarashi S, Li YF, Zhou BY, Gui DC, Endo K, Tanaka H, Chen ZH, Zhou LS, Fan MZ, Yang BX, Weissenbach J, Wang GX, Tsuji S. Machado-Joseph disease in four Chinese families: molecular analysis of 15 patients including 2 juvenile cases and its clinical correlations. Neurology 1997; 48:482-485.  

3. Zhou YX, Wang GX, Tang BS, Li WD, Wang DA, Lee HS, Sambuughin N, Zhou LS, Tsuji S, Yang BX, Goldfarb LG. Spinocerebellar ataxia type 2 in China: molecular analysis and genotype-phenotype correlation in nine families. Neurology 1998; 51: 595-598. 

4. Zhou YX, Xu X, Chen L, Li C, Brodie SG, Deng CX. A proline to arginine substitution at codon 252 (pro252arg) in fibroblast growth factor receptor 1 (FGFR1) promotes premature intramembranous ossification and results in Pfeiffer syndrome. Human Molecular Genetics, 2000; 9:2001-2008. 

5. Gaspar C, Lopes-Cendes I, Hayes S, Goto J, Arvidsson K, Dias A, Silveira I, Maciel P, Coutinho P, Lima M, Zhou YX, Soong BW, Watanabe M, Giunti P, Stevanin G, Riess O, Sasaki H, Hsieh M, Nicholson GA, Brunt E, Higgins JJ, Lauritzen M, Tranebjaerg L, Volpini V, Wood N, Ranum L, Tsuji S, Brice A, Sequeiros J, Rouleau GA. Ancestral origins of the Machado-Joseph disease mutation: a worldwide haplotype study. Am J Hum Genet. 2001, 68(2):523-8. 

6. Zhou YX, Qiao WH, Gu WH, Xie H, Tang BS, Zhou LS, Yang BX, Takiyama Y, Tsuji S, He HY, Deng CX, Goldfarb LG, Wang GX. Spinocerebellar ataxia type 1 in China: molecular analysis and genotype-phenotype correlation in five families. Archives of Neurology 2001, 58:789-794. 

7. Zhou YX, Zhao M, Shimazu M, Sakata K, Deng CX, Lu B. Cerebellar Deficits and Hyperactivity in Mice Lacking  Smad4. J. Bio Chem, 2003, 278: 42313-42320. 

8. Li SH, Yu ZX, Li CL, Nguyen HP, Zhou YX, Deng CX, and  Li XJ. Lack of Huntingtin-Associated Protein-1 Causes Neuronal Death Resembling Hypothalamic Degeneration in Huntington's Disease. J. Neurosci. 2003;23: 6956-6964 

9. Gu WH, Ma H, Wang K, Jin M, Zhou YX, Liu X, Wang G, Shen Y. The Shortest Expanded Allele of the MJD1 Gene in a Chinese MJD Kindred with Autonomic Dysfunction. Eur Neurology 2004; 52: 107-111   

10. Jiang HTang BXia KZhou YXXu BZhao GLi HShen LPan QCai F. Spinocerebellar ataxia type 6 in Mainland China: molecular and clinical features in four families. J Neurol Sci. 2005; 236: 25-29. 

11. Murtie JC, Zhou YX, Le TQ, Vana AC, Armstrong RC.  Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination. Neurobiol Dis. 2005; 19:171-182. 

12. Murtie JC, Zhou YX, Le TQ, Armstrong RC. Fibroblast growth factor 2 (FGF2) inhibits differentiation of oligodendrocyte progenitors during myelination and remyelination. Glia 2005; 49: 542-54 

13. Gu WH, Wang GX, Xiao J, Wang MY, Zhou YX. Clinical and Genetic Analysis of a Large Chinese Family with Myoclonic Epilepsy, Intention Tremors and Ataxia. Chin J Neurology, 2006; 39:399-402.  

14. Zhou YX, Flint NC, Murtie JC, Le  TQ, Armstrong RC. Retroviral Lineage Analysis of Fibroblast Growth Factor (FGF) Receptor Signaling in FGF2 Inhibition of Oligodendrocyte Progenitor Differentiation. Glia, 2006, 54:578-590. 

15. Armstrong RC, Le TQ, Flint NC, Vana AC, Zhou YX. Endogenous cell repair of chronic demyelination. Journal of Neuropathology and Experimental Neurology. 2006; 65:245-256.  

16. Zhou YX and Armstrong RC. Interaction of Fibroblast Growth Factor 2 (FGF2) and Notch Signaling Components in Inhibition of Oligodendrocyte Progenitor (OP) Differentiation. Neuroscience letter, 2007; 421:27-32.  

17. Zhao M, Li D, Shimazu K, Zhou YX, Lu B, Deng CX. Fibroblast Growth Factor Receptor-1 Is Required for Long-Term Potentiation, Memory Consolidation, and Neurogenesis. Biol Psychiatry, 2007; 62:381-390. 

18. Dobson NRZhou YXFlint NCArmstrong RC. Musashi1 RNA-binding protein regulates oligodendrocyte lineage cell differentiation and survival. Glia, 2008, 56:318-330. 

19. Zhou YX, Pannu R, Le TQ, Armstrong RC. FGFR1 Modulation Regulates Repair Capacity of Oligodendrocyte Progenitor Cells Following Chronic Demyelination. Neurobiol Dis. 2012, 45:196-205. 

20. Mierzwa  AJ, Zhou YX,  Hibbits N,  Vana AC,  Armstrong RC. FGF2 and FGFR1 signaling regulate functional recovery following cuprizone demyelination. Neuroscience Letters, 2013548: 280-285 

21. Zhou YX, Fox D, Anand A, Elhaj A, Kapoor A, Najibi F, Kim H, Weir R, Jayam-Trouth A. Artery of Percheron Infarction as an Unusual Cause of Korsakoff's Syndrome. Case Reports in Neurological Medicine, 2015  

22. Zhou YXAnand A, Najibi F, Temesgen F, Patel M, Katz D, Weir R, Dunlap S, Jayam-Trouth A. Varicella-Zoster Virus (VZV) Reactivation Resulting in Stroke and Myelitis. Annals of Neurology, 140th ANA meeting abstract issue, 2015 

23. Anand A, Zhou YXNajibi F, Weir R, Dunlap S, Jayam-Trouth A. Unusual Clinical Presentation/Reactivation of Herpes Simplex Virus Encephalitis after cranioplasty eight years ago. Epilepsia, 69th AES meeting abstract issue, 2015 

24. Zhou YXAnand A, Najibi F, Dunlap S, Weir R, Jayam-Trouth A. Cerebral venous sinus thrombosis (CVST) associated with methylenetetrahydrofolate reductase (MTHFR) A1298C mutation during early pregnancy: case report and literature review. Annals of Neurology, 2016, 80 (suppl 20): S133 

25. Zhou YX, Pfeiffer M, Elhaj A, Ali-Eltom M, Fox D, Balish M, Weir R, Jayam-Trouth A. Jerky dystonic shoulder after posterior thalamic infarction: two cases report and literature review. Annals of Neurology, 2016, 80 (suppl 20): S139 

26. Zhou YXAnand A, Najibi F, Patel M, Katz D, Weir R, Dunlap S, Jayam-Trouth A. Varicella-zoster virus reactivation resulting in stroke and progressive outer retinal necrosis: case report and literature review.  EC Neurology, 2017, 6.5: 238-242 

27. Ankrah NK, Zhou YX, Weir R, Jayam-Trouth A. Bilateral occipital infarction presenting as Anton-Babinski Syndrome and Charles Bonnet Syndrome. EC Neurology, 2017, 7.2: 40-45 

28. Cen Z, Chen Y, Yang D, Zhu Q, Chen S, Chen X, Wang B, Xie F, Ouyang Z, Jiang Z, Fu A, Hu B, Yin H, Qiu X, Yu F, Du X, Hao W, Liu Y, Wang H, Wang L, Yu X, Xiao Y, Liu C, Xiao J, Zhou Y, Yang W, Zhang B, Luo W. Intronic (TTTGA) n insertion in SAMD12 also causes familial cortical myoclonic tremor with epilepsy. Mov Disord, 2019, 34 :1571-1576. 

29. Zhou YX, Sood R, Wang Q, Carrington B, Park M, Young A, Birnbaum D, Liu Z, Ashizawa T, Mullikin J, Koubeissi M, and Liu P. Clinical and Genomic Analysis of a Large Chinese Family with Familial Cortical Myoclonic Tremor with Epilepsy and SAMD12 Intronic Repeats Expansion. Epilepsia Open, 2021, 6 :102-111. 


Ratings and reviews

  • Provider explained things understandably

  • Provider listened carefully

  • Provider knew medical history

  • Provider showed respect

  • Provider spent enough time with patient

  • Apr 28, 2022

    Not pleasant nor did I feel he really cared and insisted I was depressed because when I walked to room never had met him with mask on I did say his to him turned sideways talking to someone else. That was rude and I was in pain surgery last month hurt to walk yet I was pleasant and felt not listened too -

  • Mar 25, 2022

    Not sure of my treatment outcome yet.

  • Mar 24, 2022

    My entire visit was good and I look forward to my next visit