Jeffrey A. Toretsky, MD| Pediatric Hematology Oncology, Pediatric Hematology | MedStar Health
About me
Jeffrey A. Toretsky, MD, serves as chief of MedStar Georgetown University Hospital’s Division of Pediatric, Adolescent, and Young Adult Hematology/Oncology. Dr. Toretsky is an internationally recognized expert in sarcomas in children, adolescents, and young adults. He is the principal investigator and director of the NIH-funded Molecular Oncology Program at the Georgetown Lombardi Comprehensive Cancer Center and co-leads a regional multidisciplinary sarcoma clinic.
Dr. Toretsky and a multidisciplinary team are engaged with all aspects of pediatric hematology/oncology from diagnosis through survivorship. His laboratory is pursuing new and targeted therapies for Ewing sarcoma, including a new medication for Ewing sarcoma currently in phase 1 clinical trials.
Dr. Toretsky’s areas of clinical expertise include:
- Sarcoma
- Diagnosis and treatment of rare tumors
- Benign and malignant hematology
- Brain tumors
- Other childhood, adolescent and young adult tumors
Learn more about Toretsky Lab here.
Clinical areas of focus
- Biological Targeted Therapy
- Bone Sarcoma
- Cancer Chemotherapy
- Cancer Survivor
- Ewings Sarcoma
- Germ Cell Tumor
- Leukemia
- Lymphoma
- Musculoskeletal Tumor
- Osteosarcoma
- Rhabdomyosarcoma
- Sarcoma
- Sickle Cell Disease
Conditions and procedures
Conditions I treat
- Abdominal Pain
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myelogenous Leukemia (AML)
- Adamantinoma
- Adverse Effects To Anticoagulants
- Alveolar Soft Part Sarcoma
- Anaplastic Cancer Of Thyroid
- Anemia
- Anemia Of Chronic Disease
- Angiomatoid Fibrous Histiocytoma
- Angiosarcoma
- Antithrombin Deficiency
- Aplastic Anemia
- Askin's Tumor
- Atypical Lipomatous Tumor
- B12 Deficiency Anemia
- Back Pain
- Beckwith Wiedemann Syndrome
- Bleeding Disorder
- Blood Cancer
- Blood Clotting Disorder
- Blood Disorders
- Bone Cyst
- Bone Marrow Disorders
- Bone Sarcoma
- Bone Tumor
- Brain Neoplasms
- Burkitt Lymphoma
- Cancer
- Cancer Pain
- Cancer Related Fatigue
- Cancer Survivor
- Cardiac Sarcoma
- Cardio Oncology
- Cervical Teratoma
- Chondrosarcoma
- Chronic Fatigue
- Chronic Pain
- Clear Cell Sarcoma
- Cloves Syndrome
- Composite Hemangioendothelioma
- Cooley Anemia
- Cryoglobulinemia
- Delayed Menarche
- Delayed Puberty
- Dermatofibrosarcoma Protruberans
- Desmoid Tumors
- Desmoplastic Small Cell Tumor
- Desmoplastic Small Round Cell Tumors
- Diamond Blackfan Anemia
- Diffuse Intrinsic Pontine Glioma (DIPG)
- Dyskeratosis Congenita
- Dysmenorrhea
- Ectomesenchymoma
- Egfr Mutation
- Endocrine Complications Of Cancer Therapy
- Epithelioid Hemangioendothelioma
- Epithelioid Sarcoma
- Ewings Sarcoma
- Extrarenal Rhabdoid Tumor
- Extraskeletal Mesenchymal Chondrosarcoma
- Extraskeletal Myxoid Chondrosarcoma
- Extraskeletal Osteosarcoma
- Factor Eight Disorder
- Factor Nine Deficiency
- Factor V Leiden
- Familial Aplastic Anemia
- Fanconi Anemia
- Fibrosarcoma
- Fibrosarcoma Of The Head & Neck
- Follicular Cancer Of Thyroid
- Germ Cell Tumor
- Germinoma
- Giant Cell Tumor Of The Bone
- Glioma
- Glucose 6 Phosphate Dehydrogenase Deficiency
- Granulation Cell Sarcoma
- Head And Neck Tumors
- Headache
- Hemochromatosis
- Hemoglobinopathies
- Hemolytic Anemia
- Hemolytic Disease Of The Fetus
- Hemolytic Uremic Syndrome
- Hemophilia
- Heparin Induced Thrombocytopenia
- Hereditary Cancer Risk
- Hereditary Spherocytosis
- Histiocytosis
- Hypercoagulable State
- Hypogammaglobulinemia
- Idiopathic Thrombocytopenic Purpura
- Inflammatory Myofibroblastic Tumor
- Intimal Sarcoma
- Iron Deficiency Anemia
- Irregular Menstruation
- Juvenile Myelomonocytic Leukemia
- Kasabach Merritt Phenomenon (KMP)
- Langerhans Cell Histiocytosis
- Leiomyosarcoma
- Leukemia
- Leukopenia
- Li Fraumeni Syndrome
- Liposarcoma
- Low Grade Fibromyxoid Sarcoma
- Lymphangiosarcoma
- Lymphoma
- Lymphopenia
- Malignant Fibrous Histiocytoma (MFH)
- Malignant Glomus Tumor
- Malignant Granular Cell Tumor
- Malignant Mesenchymoma
- Malignant Peripheral Nerve Sheath Tumor
- Malignant Primitive Neuroectodermal Tumor (PNET)
- Malignant Rhabdoid Tumor
- Malignant Schwannoma
- Malignant Tenosynovial Giant Cell Tumor
- Malnutrition
- Medullary Cancer Of Thyroid
- Menorrhagia
- Menstrual Disorders
- Musculoskeletal Tumor
- Myelodysplastic Syndrome
- Myeloproliferative Diseases
- Myoepithelioma/Mixed Tumor Of Soft Tissue
- Myofibroblastic Sarcoma
- Myxofibrosarcoma
- Myxoinflammatory Fibroblastic Sarcoma
- Nephroblastoma
- Neuroblastoma
- Neuroectodermal Tumor
- Neurofibrosarcoma
- Neuronal Glial Tumors
- Neutropenia
- Non Hodgkin Lymphoma
- Odontogenic Tumors
- Optic Pathway Glioma
- Oral Complications Of Cancer
- Oral Lesions
- Osteosarcoma
- Pancytopenia
- Papillary Cancer Of Thyroid
- Paroxysmal Nocturnal Hemoglobinuria
- Pecoma
- Pediatric Cancer
- Pelvic Pain
- Pernicious Anemia
- Petechiae
- Peutz Jeghers Syndrome
- Plasma Cell Dyscrasia
- Pleomorphic Sarcoma
- Pleomorphic Xanthoastrocytomas
- Polycystic Ovary Syndrome
- Polycythemia
- Porphyria
- Primary Systemic Amyloidosis
- Pulmonary Metastases
- Pure Red Cell Aplasia
- Purpura
- Radiation Associated Sarcomas
- Retiform Hemangioendothelioma
- Retinoblastoma
- Retroperitoneal Mass
- Retroperitoneal Sarcoma
- Rh Incompatibility
- Rhabdomyosarcoma
- Sacrococcygeal Teratoma
- Sarcoma
- Sarcoma Botryoides
- Sarcoma Of The Lung
- Scoliosis
- Secondary Polycythemia
- Severe Congenital Neutropenia
- Sickle Cell Disease
- Side Effects Of Cancer Treatment
- Solitary Fibrous Tumor
- Spindle Cell Sarcoma
- Splenic Sequestration
- Splenomegaly
- Sports Related Injury
- Submucosal Tumors
- Sweat Gland Carcinoma
- Synovial Sarcoma
- Tectal Glioma
- Teratogen Exposure
- Thalassemia
- Thrombocytopenia
- Thrombocytosis
- Thrombophilia
- Thrombotic Thrombocytopenic Purpura
- Tracheal Cancer
- Unclassified Sarcoma
- Undifferentiated Pleomorphic Sarcoma
- Undifferentiated Sarcoma
- Venous Occlusive Crisis
- Von Willebrand Disease
- Weight Loss
Procedures I perform
- Adjuvant Chemotherapy
- Biological Targeted Therapy
- Brain Cancer Genomics
- Breast Cancer Immunotherapy
- Cancer Chemotherapy
- Cancer Genomics
- Cancer Immunotherapy
- Cancer Rehabilitation
- Chemoradiation
- Early Detection Of Cancer
- Gastrointestinal (GI) Cancer Genomics
- Genitourinary Cancer Genomics
- Head And Neck Cancer Genomics
- Leukemia Genomics
- Liver Cancer Genomics
- Lymphoma Genomics
- Melanoma Genomics
- Pancreatic Cancer Genomics
- Pediatric Stem Cell Collection For Transplant
- Radionuclide Therapy
- Renal Cancer Genomics
- Sarcoma Genomics
- Skin Cancer Genomics
- Thyroid Cancer Genomics
Practice locations
Distance from Change LocationEnter your Location
3800 Reservoir Road Northwest Lombardi Cancer Center Washington, DC, 20007
202-444-2223Fax 202-444-1229
Insurance
MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.
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List of insurance plans we accept
- Cigna HealthSpring Medicare Advantage
- Aetna Better Health of Maryland
- Blue Choice Advantage & Healthy Blue (HMO, POS)
- UnitedHealthcare and AARP Medicare Complete Plans/ UHC Group Medicare Advantage Plans HMO, POS, PPO
- United Healthcare Options (PPO) (includes Empire PPO, GEHA, Compass Rose)
- UnitedHealthcare Medicare Adv/Special Needs Plans
- UHC Community Plan of MD
- Private Health Care Systems (PHCS) (PPO)
- Medicare Fee for Service
- Kaiser Virginia Premier
- Kaiser PermanenteSelect-Added Choice
- Kaiser Permanente Signature-Added Choice
- Kaiser Permanente Signature
- Kaiser Permanente Select
- Kaiser Permanente Medicare Plus (Medicare Supplemental Plan)
- Kaiser Permanente Flexible Choice POS
- Kaiser MD Medicaid MCO
- CFBCBS Federal Employee Program (Std/Basic PPO/Blue Focus)
- CFBCBS EPO
- Aetna Innovations: HMO & EPO Plus
- Select HMO/HealthFund/Health Network
- Aetna HMO
- Open POS II
- Innovation Health: Open POS Plus
- Choice POS & Choice POS II
- Aetna Managed Choice Open Access (POS)
- Open EPO Plus
- Opoen HMO Option
- Open HMO
- Innovation Health: POS
- Aetna HMO-Open Access/Select OA/HealthFund/Health Network Option OA
- Innovation Health: Open Network Only Plus
- Aetna Elect Choice/ Open Access (POS)
- Innovation Health: POS Plus
- Aetna Managed Choice (POS)
- Innovation Health: PPO
- Aetna Open Choice (PPO)
- Innovation Health: Indemnity
- Aetna Traditional Choice (PPO)
- BlueChoice Open Access
- CFBCBS Blue Choice Opt Out Open Access
- HealthyBlue PPO
- CFBSBC Blue Preferred PPO
- Choice Fund PPO
- PPO and PPO Plus
- CIGNA EPO
- POS OA & OA Plus
- Network OA
- CIGNA HMO Open Access (OA)
- United Healthcare Choice
- CIGNA POS/Network POS
- CFBCBS Blue Choice Opt Out Plus Open Access (POS)
- Tricare Prime
- CFBCBS BlueChoice HMO
- MedStar Family Choice - Maryland Health Choice
- Aetna Quality Point of Service (POS)
- United Student Resources
- Tricare for Life (Medicare Supplemental Plan)
- United Healthcare Choice Plus
- CFBCBS Maryland Point of Service Plan (MPOS)
- Coventry of Delaware HMO/PPO
- Aetna Elect Choice/ EPO (Aetna Health Fund) Innovation Health: Network Only Plus
- Coventry Health Care of Virginia
- Aetna Worker's Compensation Network
- United Healthcare Select Plus (POS)
- United Healthcare Select HMO - EPO/NPP
- Coventry Health Care National Network PPO
- CFBCBS Maryland Indemnity or PPO
- First Health PPO
- Aetna Medicare Advantage HMO & PPO Plans
- CFBCBS (NCA) Indemnity
- Optimum Choice Preferred (POS) & OCI Direct (HMO)
- M.D. IPA (HMO)
- CIGNA HMO & Network (HMO)
- Aetna Student Health Insurance
- CIGNA Indemnity
- Great-West Healthcare POS/CIGNA
- M.D. IPA Preferred (POS)
- FIRST HEALTH
- Mamsi Life & Health (Indem./PPO)
- MedStar Select (MedStar Associates' Plan)
Videos
Education
Board Certification: American Board of Pediatrics, Pediatrics
Fellowship: National Cancer Institute (1997)
Residency: Medical College of Virginia Hospitals (1991)
Medical School: University of Minnesota Medical School Office of the Registrar (1988)
Awards
- Fellow, National Academy of Inventors, 2018
- Outstanding Faculty Entrepreneur in Medical Science, Georgetown Business School, 2012
- Georgetown University Medical Center Convocation Honoree for Outstanding Research, 2009
- National Academies Keck Futures Initiatives Conference, 2009
- Georgetown University Medical Center Convocation Honoree, 2008
- Burroughs Wellcome Clinical Scientist Award in Translational Research, 2008
Hospital affiliations
News and publications
- Anderson ND, de Borja R, Young MD, Fuligni F, Rosic A, Roberts ND, Hajjar S, Layeghifard M, Novokmet A, Kowalski PE, Anaka M, Davidson S, Zarrei M, Id Said B, Schreiner LC, Marchand R, Sitter J, Gokgoz N, Brunga L, Graham GT, Fullam A, Pillay N, Toretsky JA, Yoshida A, Shibata T, Metzler M, Somers GR, Scherer SW, Flanagan AM, Campbell PJ, Schiffman JD, Shago M, Alexandrov LB, Wunder JS, Andrulis IL, Malkin D, Behjati S, Shlien A. Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors. Science. 2018 Aug 31;361(6405). PubMed PMID: 30166462. Pubmed Central PMCID: 6176908.
- Gorthi A, Romero JC, Loranc E, Cao L, Lawrence LA, Goodale E, Iniguez AB, Bernard X, Masamsetti VP, Roston S, Lawlor ER, Toretsky JA, Stegmaier K, Lessnick SL, Chen Y, Bishop AJR. Author Correction: EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma. Nature. 2018 Jul;559(7715):E11. PubMed PMID: 29950716.
- Smith-Guzman NE, Toretsky JA, Tsai J, Cooke RG. A probable primary malignant bone tumor in a pre-Columbian human humerus from Cerro Brujo, Bocas del Toro, Panama. International journal of paleopathology. 2018 Jun;21:138-46. PubMed PMID: 29778411.
- Selvanathan SP, Graham GT, Grego AR, Baker TM, Hogg JR, Simpson M, Batish M, Crompton B, Stegmaier K, Tomazou EM, Kovar H, Uren A, Toretsky JA. EWS-FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex. Nucleic acids research. 2019 Oct 10;47(18):9619-36. PubMed PMID: 31392992. Pubmed Central PMCID: 6765149.
- Spriano F, Chung EYL, Gaudio E, Tarantelli C, Cascione L, Napoli S, Jessen K, Carrassa L, Priebe V, Sartori G, Graham G, Selvanathan SP, Cavalli A, Rinaldi A, Kwee I, Testoni M, Genini D, Ye BH, Zucca E, Stathis A, Lannutti B, Toretsky JA, Bertoni F. The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Aug 15;25(16):5167-76. PubMed PMID: 31182435.
- Ko, K., Kitani, T., Harris, B. T., Anaizi, A. N., Solomon, D., Perry, A., Toretsky, J. and Ozdemirli, M. A novel PARD3B-NUTM1 fusion in an aggressive primary CNS embryonal tumor in a young adult. Acta Neuropathol Commun. 2020 Jul 17;8(1):112. doi: 10.1186/s40478-020-00991-w.
- Pecora, A., Halpern, S., Weber, M., Paleoudis, E. G., Panush, D., Patterson, F. and Toretsky, J. Rapid and Complete Response to Combination Anti-CTLA-4 and Anti-PD-1 Checkpoint Inhibitor Therapy in a Patient With Stage IV Refractory End-stage Epithelioid Sarcoma: A Case Report. J Immunother. 2020 Nov/Dec;43(9):286-290. doi: 10.1097/CJI.0000000000000332.
- J. Dong, R. Y. Zhang, N. Sun, J. Hu, M. D. Smalley, A. Zhou, Y. Hua, W. Rothermich, M. Chen, J. Chen, J. Ye, P.-C. Teng, D. Qi, J. A. Toretsky, J. S. Tomlinson, M. Li, P. S. Weiss, S. J. Jonas, N. Federman, L. Wu, M. Zhao,* H.-R. Tseng,* Y. Zhu. Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma‐Derived Extracellular Vesicles for Downstream Functional Studies. Advanced Functional Materials. 2020 September 13; https://doi.org/10.1002/adfm.202003237.
For complete list: http://www.ncbi.nlm.nih.gov/pubmed/?term=Toretsky+J