Louis Marc Weiner, MD| Gastrointestinal Medical Oncology, Medical Oncology | MedStar Health
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Louis Marc Weiner

Louis Marc Weiner, MD
Provider is directly employed by MedStar Health

4.8 out of 5 (118 reviews)

Specialties: Gastrointestinal Medical Oncology, Medical Oncology

Languages: English

202-444-1229

About me

Dr. Weiner is an internationally-recognized medical oncologist specializing in gastrointestinal cancers. He is also an accomplished researcher developing novel immunotherapy treatments – essentially triggering the body’s own immune system to identify and destroy cancer. He is recognized for his laboratory and clinical research focusing on these new therapeutic approaches. Dr. Weiner wants to understand why some tumors become resistant to therapy and other forms of cancer immunotherapy, with the goal of developing new treatments to overcome that resistance. He lectures extensively on these forms of targeted therapies, which block the growth and spread of cancer.

He serves as director of the Georgetown Lombardi Comprehensive Cancer Center – Washington, D.C.’s only National Cancer Institute-designated comprehensive cancer center – and the MedStar Georgetown Cancer Institute, which combines medical expertise, the latest therapies, and research across MedStar Health throughout the region. Dr. Weiner is also associate vice president at Georgetown University Medical Center, chair of the oncology department at Georgetown University School of Medicine, and clinical director of cancer services at MedStar Georgetown University Hospital.

In these roles, Dr. Weiner is responsible for operations, development, research, clinical and educational missions. As the Institute’s director, he oversees the clinical operations of the MedStar Health cancer service line, and leads the advancement of clinical care and research programs spanning prevention, treatment, rehabilitation, survivorship and end-of-life care across the region. With Georgetown Lombardi serving as the Institute’s “research engine,” patients throughout the region have access to unmatched expertise and clinical trials closer to where they live and work.

Dr. Weiner previously served as chairman of the Medical Oncology Department and vice president for Translational Research at Fox Chase Cancer Center in Philadelphia, PA. He held an endowed chair in medical science and was the driving force behind developing an immunotherapy laboratory and clinical programs, as well as establishing the Center's medical oncology fellowship program. Dr. Weiner also served as professor in the Department of Medicine at Temple University School of Medicine.

Dr. Weiner's Philosophy of Care
We live in a time of great hope in the area of cancer therapy. Many new, important and life-changing treatments are now being developed. We are privileged to offer patients tomorrow's treatments today. And now, through the MedStar Georgetown Cancer Institute, we can extend that mission across the region. With this progress in mind, I strive to offer all my patients the best possible therapies for their diseases, always mindful that I am neither treating a disease nor a patient, but a person with a life, a family and a combination of hopes and fears.

Working at a great cancer program like this gives me the opportunity to collaborate with leading international experts to assure that my patients can benefit from the best possible care during the course of their journeys.

Clinical areas of focus

  • Esophageal Cancer Treatment
  • Gastrointestinal Cancer Treatment
  • Liver Metastases Treatment
  • Low Anterior Resection
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Procedures I perform

  • A1c Testing
  • Adjuvant Hormone Therapy
  • Akt Inhibitors
  • Anemia Management
  • Angiogenesis Inhibitors
  • Antiangiogenic Therapy
  • Aromatase Inhibitors
  • Arthrocentesis
  • Barium Enema
  • Bavituximab
  • Bioinformatics
  • Blinatumomab
  • Blood Banking
  • Brca Gene Testing
  • Cancer Biotechnology
  • Cancer Research Institute
  • Cancer Survivorship
  • Cancer Systems Biology
  • Cardiac Gene Expression
  • Chemoradiation
  • Chemotherapy Administration
  • Cholecystectomy
  • Cisplatin
  • Clinical Pathology
  • Clinical Trials
  • Coagulopathy Management
  • Cold Laser Therapy
  • Colectomy
  • Colorectal Cancer Treatment
  • Community Health
  • Crispr-Cas9
  • Disease Prevention
  • Embolization For Bleeding
  • Endoscopic Mucosal Resection
  • Enteroscopy
  • Esophageal Cancer Treatment
  • Fertility Counseling
  • Gastrectomy
  • Gastrointestinal Cancer Treatment
  • Gemtuzumab Ozogamicin
  • Genomic Instability
  • Genomic Testing For Cancer
  • Growth Hormone Management With Octreotide
  • Health Outcomes Research
  • Helicobacter Pylori Stool Test
  • Hepatectomy
  • Hepatic Artery Infusion
  • Hepatoblastoma Treatment
  • Hormone Regulation With Leuprolide
  • Hormone Replacement Therapy
  • Ileal Pouch-Anal Anastomosis
  • Immunotherapy
  • Intravenous (IV) Fluids
  • Isolated Limb Perfusion
  • Laparoscopic Revision Of Gastric Restrictive Procedure
  • Lhrh Agonists
  • Liquid Biopsy
  • Liver Cancer Treatment
  • Liver Metastases Treatment
  • Low Anterior Resection
  • Lynch Syndrome Testing
  • Magnetic Resonance Imaging (MRI)
  • Minimally Invasive Surgery
  • Molecular Diagnostics
  • Nateglinide
  • Neoadjuvant Therapy
  • Neratinib
  • Nod-Like Receptor Monitoring
  • Pancreatectomy
  • Pancreatic Cancer Treatment
  • Pegargiminase
  • Pegilodecakin
  • Peginterferon Alfa-2A
  • Percutaneous Tumor Chemoembolization
  • Performance Improvement
  • Perianal Surgery
  • Peripheral Blood Stem Cell Transplantation
  • Personalized Care
  • Pertuzumab
  • Pet-Ct Scan
  • Pharmacokinetics
  • Pharmacological Treatment Of Hypertension
  • Portosystemic Shunt
  • Pre-Operative Conditioning
  • Radiomics
  • Removal Of Central Venous Access Device
  • Rilotumumab
  • Rituximab
  • Robotic Surgery
  • Selpercatinib
  • Single Photon Emission Computed Tomography
  • Sintilimab
  • Stem Cell Gene Editing
  • Stem Cell Therapy
  • Stereotactic Ablative Radiotherapy
  • Stivarga
  • Synthetic Lethality
  • Tertiary Cancer Prevention
  • Tocilizumab (ACTEMRA) Treatment
  • Tofacitinib (XELJANZ) Treatment
  • Total Proctocolectomy
  • Translational Medicine Research
  • Transplant Immunology
  • Trastuzumab
  • Trastuzumab Emtansine
  • Tumor Marker Testing
  • Ultrasound
  • Vaccinations
  • Vectibix
  • Wellness Services
  • Whole-Exome Sequencing
  • Ziv-Aflibercept
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Practice locations

Distance from Change Location Enter your Location

3800 Reservoir Rd NW
Lombardi Cancer Center
Washington, DC, 20007

202-444-2223
Get Directions

miles away

Fax 202-444-1229

Insurance

MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.

  • List of insurance plans we accept
    • Aetna Traditional Choice (PPO)
    • Advantra Platinum (PPO)
    • TRICARE East Prime
    • CareFirst Group Medicare Advantage
    • Jai Medical Systems - Maryland Health Choice
    • CareFirst NASCO
    • Anthem BCBS of VA Key Care POS/PPO/Indemnity
    • Aetna Classic 3500
    • Fee-for-Service (FFS) District of Columbia, Maryland and Virginia Medicaid
    • CareFirst BlueChoice HMO
    • CareFirst Dual Prime HMO-SNP
    • Optimum Choice
    • Humana Medicare Advantage - PPO
    • HumanaChoice PPO
    • Choice POS II
    • Choice Care Network/HUMANA (PPO)
    • Kaiser Permanente Medicare Plus
    • Optimum Choice & Optimum Choice Preferred (POS) Cardiac Global
    • CareFirst EPO
    • BlueChoice Open Access
    • Kaiser Permanente Select
    • IH-Open Network Only Plus
    • CareFirst Administrators
    • Beech Street PPO
    • CareFirst MedStar Select PPO
    • Kaiser Permanente Select Cardiac Global
    • CareFirst Maryland Indemnity or PPO
    • Coventry of Delaware HMO/PPO
    • MedStar Family Choice DC Healthy Families
    • Anthem BCBS Medi Blue Dual Adv
    • Police and Fire Clinic
    • Aetna Basic
    • Aetna Medicare Advantage PFFS Plan
    • Great-West Healthcare POS/CIGNA
    • Cigna Preferred Medicare (HMO)
    • UnitedHealthcare Medicare Adv. Special Needs Plans
    • CIGNA EPO
    • Alterwood Advanatge HMO & DSNP Plans
    • Aetna Worker's Compensation Network
    • Magellan Complete Care of VA - VA Medicaid MCO
    • UnitedHealthcare Individual Exchange Plans
    • United Medicare Private Fee-for-Service (PFFS) plans
    • Aetna Advantage 6350PD
    • First Health PPO
    • Private Health Care Systems (PPO)
    • First Health PPO
    • Options PPO Cardiac Global
    • IH-EPO Plus
    • IH-POS
    • Choice POS II Open Access
    • CareFirst MedStar PPO
    • IH-Open HMO Option
    • Aetna VA Exchange
    • IH-Open EPO Plus
    • Humana Gold Plus HMO
    • Aetna Elect Choice/ EPO (Aetna Health Fund)
    • Aetna Signature Administrator PPO/TPA
    • MD IPA (HMO) & MD IPA Preferred Cardiac Global
    • UnitedHealthcare and AARP Medicare Complete Plans
    • IH-Open POS II
    • United Healthcare Choice Plus
    • CareFirst Maryland Point of Service Plan
    • OA Plus
    • Aetna Classic 5000PD
    • Aetna Elect Choice/ Open Access (POS)
    • Aetna Managed Choice Open Access (POS)
    • Aetna Managed Choice (POS)
    • TRICARE East Select
    • Cigna TotalCare (HMO D-SNP)
    • Cigna Achieve Medicare (HMO C-SNP)
    • Uniformed Services Family Health Plan
    • Anthem BCBS of VA HealthKeepers (HMO)
    • AMERIVANTAGE/Amerigroup Community Care
    • M.D. IPA (HMO)
    • Kaiser Permanente HMO Plus and DHMO Plus Member
    • DC/MD SHOP QHP Small Business Plans
    • CareFirst (NCA) Indemnity
    • Anthem BCBS Medi Blue SNP
    • MultiPlan, Inc
    • OCI Direct (HMO)
    • BCBS of Michigan (BCN Advantage,Security Blue, Freedom, Medicare PLUS Blue Group PPO)
    • MedStar Family Choice - Maryland Health Choice
    • CIGNA Connect EPO
    • CareFirst Group Medicare Advantage prescription drug benefit (PPO)
    • United Healthcare Select HMO - EPO/NPP
    • HUMANA/Choice Care Medicare Plans (Choice, Gold Choice)
    • Kaiser Maryland Medicaid MCO
    • Aetna HMO
    • Aetna Student Health Insurance
    • Anthem Federal Employee Program Standard
    • United Healthcare Options (PPO)
    • CareFirst Blue Choice Opt Out Open Access
    • CIGNA PPO
    • TRICARE for Life East
    • Aetna Medicare Advantage HMO & PPO Plans
    • AmeriHealth Caritas DC Healthcare Alliance
    • Kaiser Permanente Signature
    • Kaiser Permanente Flexible Choice POS Cardiac Global
    • United Healthcare Choice Cardiac Global
    • Amerigroup DC Alliance
    • Blue Choice Advantage
    • CIGNA HMO Open Access
    • CIGNA PPO Plus
    • Kaiser Permaenete Signature - Added Choice Cardiac Global
    • Cigna True Choice Plus Medicare (PPO)
    • Aetna Premier 200PD
    • Aetna Quality Point of Service (POS)
    • Aetna Better Health of MD
    • Sentara Health
    • BCBS Out-of-State Medicare Plans (Blue Advantage)
    • NYC Medicare Advantage Plus
    • Anthem BCBS Medi Blue Plus
    • Healthy Blue (HMO, POS)
    • Maryland Physicians Care MCO
    • IH-HMO
    • CareFirst Community Health Plan of MD
    • Health Services for Children with Special Needs
    • United Healthcare Select Plus (POS)
    • Mamsi Life & Health (Indem./PPO)
    • IH-PPO
    • Medicare Advantage - Advantra Value (PPO)
    • HumanaChoice Honor's plan PPO
    • Priority Partners - Maryland Health Choice
    • Johns Hopkins Advantage MD PLUS PPO
    • United Student Resources
    • Aetna Classic 5000
    • United Healthcare Choice Plus Cardiac Global
    • Network OA
    • MedStar Family Choice DC Healthcare Alliance
    • Medicare Direct
    • United HealthCare Community Plan - Maryland Health Choice Program
    • CareFirst Blue Preferred PPO
    • UnitedHealthcare Medicare Advantage DSNP District of Columbia
    • CareFirst Blue Card Program
    • Choice POS
    • Optimum Choice Preferred (POS)
    • Lasso Healthcare - Medicare Medical Savings Account
    • Navigate
    • Anthem Federal Employee Program Basic
    • Johns Hopkins Advantage MD HMO
    • IH-Open POS Plus
    • CIGNA Indemnity
    • Veterans Affairs Community Care Network
    • Coventry Health Care National Network PPO
    • Private Fee-for-Service Plans (PFFS)
    • Aetna Open Choice (PPO)
    • CareFirst Federal Employee Program (Std. & Basic PPO)
    • Cigna Alliance Medicare (HMO)
    • M.D. IPA Preferred (POS)
    • TriWest Healthcare Alliance
    • Anthem BCBS of VA HealthKeepers (POS & POS OA)
    • United Healthcare Select HMO-EPO/NPP Cardiac Global
    • POS OA
    • IH-Network Only Plus
    • Kaiser Permanente Medicare Advantage Signature and Select
    • IH-Indemnity
    • AmeriHealth Caritas DC Healthy Families
    • Kaiser Permanente Select - Added Choice
    • Kaiser Permanente Signature - Added Choice
    • CIGNA POS/Network POS
    • Erickson Advantage Plans
    • WellPoint Maryland - Maryland Health Choice
    • HealthyBlue PPO
    • Choice Fund PPO
    • Mamsi Life & Health (Indem./PPO) Cardiac Global
    • United Healthcare Navigate Cardiac Global
    • Employee Health Plan
    • IH-POS Plus
    • Aetna Better Health of VA
    • CareFirst Blue Choice Opt Out Plus Open Access (POS)
    • Tricare Reserve Select
    • United Healthcare Choice
    • Anthem BCBS of VA HealthKeepers Plus
    • Optima Family Care MCO - VA Medicaid MCO
    • HighMark
    • Aetna HMO-Open Access/Select OA/HealthFund/Health Network Option OA
    • Coventry Health Care of Virginia
    • United Healthcare Community Plan - VA Medicaid MCO
    • Geisinger Medicare Advantage
    • Select HMO/HealthFund/Health Network
    • CareFirst FEP Blue Focus
    • Kaiser Permanente Flexible Choice 3-tier POS
    • IH-Open HMO
    • Amerigroup DC Healthy Families
    • UHC Passport
    • CIGNA SureFit (HMO)
    • CIGNA HMO & Network (HMO)
    • Humana Medicare Advantage - HMO Open Access
    • Cigna True Choice Medicare (PPO)
    • Johns Hopkins Advantage MD PPO
    • Aetna Advantage 6350
    • UHC Group Medicare Advantage Plans (HMO, POS, PPO)
    • Medicare FFS
    • CareFirst BlueCross BlueShield Advantage Core/Enhanced
    • Aetna Advantage 5750
    • Core Essential (HMO)

Videos

Education

Board Certification: American Board of Internal Medicine, Internal Medicine

Fellowship: Tufts Medical Center (1984)

Fellowship: Tufts Medical Center (1982)

Residency: University of Vermont Medical Center (1981)

Internship: University of Vermont Medical Center (1978)

Medical School: Icahn School of Medicine at Mount Sinai (1977)

Awards

  • Castle Connolly Top Doctors, 2021
  • National Academy of Inventors Fellow, 2017-2018
  • Recognition for Outstanding Contribution to Innovation and Commercialization, Georgetown University, Office of Technology, 2016
  • Fellow, American College of Physicians, 2010
  • America’s Top Oncologists, 2009               
  • America’s Top Doctors for Cancer, 2007 – Present
  • Philadelphia Magazine's Top Docs, 2002; 2004 – 2007
  • Who's Who in Medicine and Healthcare, 2002 - 2005
  • G. Morris Dorrance, Jr. Endowed Chair in Medical Science, 2002
  • American Association for Cancer Research Scientist-Survivor Program Award, 2002
  • American Cancer Society - Southeast Region Scientific Research Award, 2002
  • Janssen Pharmaceutical Research Foundation: Research Award for Outstanding Contributions to the Field of Receptor Targeted Therapy, 2001
  • Best Doctors in America, 2000-2011
  • National Cancer Institute Clinical Investigator Award, 1986
  • American Cancer Society Career Development Award, 1985

News and publications

Dr. Weiner has authored more than 200 publications throughout his career centering on the following core topics:
  • Enhancing Antibody Dependent Cellular Cytotoxicity (ADCC) as an Anti-Tumor Mechanism
  • Manipulating Antibody Structure to Improve Selective Tumor Targeting
  • Identifying Tumor Cell-Based Determinants of Antibody-Mediated Cell Killing
  • Immunoconjugates for Cancer Therapy
  • Antibody-initiated Cancer Immunotherapy
  • Click here for a complete list of his research papers and scientific contributions. 

Ratings and reviews

  • Explanations the care provider gave you about your problem or condition

    4.8
  • Extent to which the care provider listened to you

    4.8
  • Care provider’s discussion of any proposed treatment (options, risks, benefits, etc.)

    4.8
  • Provider included you in decisions

    4.8
  • Concern the care provider showed for your questions or worries

    4.8
  • Likelihood of recommending this care provider to others

    4.9
  • Jan 28, 2025

    Dr. Weiner is amazing. So knowledgeable and great people skills I am very luck to be under his care.

  • Nov 14, 2024

    Great!

  • Mar 21, 2024

    The best!