About me
Dr. Weiner is an internationally-recognized medical oncologist specializing in gastrointestinal cancers. He is also an accomplished researcher developing novel immunotherapy treatments – essentially triggering the body’s own immune system to identify and destroy cancer. He is recognized for his laboratory and clinical research focusing on these new therapeutic approaches. Dr. Weiner wants to understand why some tumors become resistant to therapy and other forms of cancer immunotherapy, with the goal of developing new treatments to overcome that resistance. He lectures extensively on these forms of targeted therapies, which block the growth and spread of cancer.
He serves as director of the Georgetown Lombardi Comprehensive Cancer Center – Washington, D.C.’s only National Cancer Institute-designated comprehensive cancer center – and the MedStar Georgetown Cancer Institute, which combines medical expertise, the latest therapies, and research across MedStar Health throughout the region. Dr. Weiner is also associate vice president at Georgetown University Medical Center, chair of the oncology department at Georgetown University School of Medicine, and clinical director of cancer services at MedStar Georgetown University Hospital.
In these roles, Dr. Weiner is responsible for operations, development, research, clinical and educational missions. As the Institute’s director, he oversees the clinical operations of the MedStar Health cancer service line, and leads the advancement of clinical care and research programs spanning prevention, treatment, rehabilitation, survivorship and end-of-life care across the region. With Georgetown Lombardi serving as the Institute’s “research engine,” patients throughout the region have access to unmatched expertise and clinical trials closer to where they live and work.
Dr. Weiner previously served as chairman of the Medical Oncology Department and vice president for Translational Research at Fox Chase Cancer Center in Philadelphia, PA. He held an endowed chair in medical science and was the driving force behind developing an immunotherapy laboratory and clinical programs, as well as establishing the Center's medical oncology fellowship program. Dr. Weiner also served as professor in the Department of Medicine at Temple University School of Medicine.
Dr. Weiner's Philosophy of Care
We live in a time of great hope in the area of cancer therapy. Many new, important and life-changing treatments are now being developed. We are privileged to offer patients tomorrow's treatments today. And now, through the MedStar Georgetown Cancer Institute, we can extend that mission across the region. With this progress in mind, I strive to offer all my patients the best possible therapies for their diseases, always mindful that I am neither treating a disease nor a patient, but a person with a life, a family and a combination of hopes and fears.
Working at a great cancer program like this gives me the opportunity to collaborate with leading international experts to assure that my patients can benefit from the best possible care during the course of their journeys.
Clinical areas of focus
- Esophageal Cancer Treatment
- Gastrointestinal Cancer Treatment
- Liver Metastases Treatment
- Low Anterior Resection
Procedures I perform
- A1c Testing
- Adjuvant Hormone Therapy
- Akt Inhibitors
- Anemia Management
- Angiogenesis Inhibitors
- Antiangiogenic Therapy
- Aromatase Inhibitors
- Arthrocentesis
- Barium Enema
- Bavituximab
- Bioinformatics
- Blinatumomab
- Blood Banking
- Brca Gene Testing
- Cancer Biotechnology
- Cancer Research Institute
- Cancer Survivorship
- Cancer Systems Biology
- Cardiac Gene Expression
- Chemoradiation
- Chemotherapy Administration
- Cholecystectomy
- Cisplatin
- Clinical Pathology
- Clinical Trials
- Coagulopathy Management
- Cold Laser Therapy
- Colectomy
- Colorectal Cancer Treatment
- Community Health
- Crispr-Cas9
- Disease Prevention
- Embolization For Bleeding
- Endoscopic Mucosal Resection
- Enteroscopy
- Esophageal Cancer Treatment
- Fertility Counseling
- Gastrectomy
- Gastrointestinal Cancer Treatment
- Gemtuzumab Ozogamicin
- Genomic Instability
- Genomic Testing For Cancer
- Growth Hormone Management With Octreotide
- Health Outcomes Research
- Helicobacter Pylori Stool Test
- Hepatectomy
- Hepatic Artery Infusion
- Hepatoblastoma Treatment
- Hormone Regulation With Leuprolide
- Hormone Replacement Therapy
- Ileal Pouch-Anal Anastomosis
- Immunotherapy
- Intravenous (IV) Fluids
- Isolated Limb Perfusion
- Laparoscopic Revision Of Gastric Restrictive Procedure
- Lhrh Agonists
- Liquid Biopsy
- Liver Cancer Treatment
- Liver Metastases Treatment
- Low Anterior Resection
- Lynch Syndrome Testing
- Magnetic Resonance Imaging (MRI)
- Minimally Invasive Surgery
- Molecular Diagnostics
- Nateglinide
- Neoadjuvant Therapy
- Neratinib
- Nod-Like Receptor Monitoring
- Pancreatectomy
- Pancreatic Cancer Treatment
- Pegargiminase
- Pegilodecakin
- Peginterferon Alfa-2A
- Percutaneous Tumor Chemoembolization
- Performance Improvement
- Perianal Surgery
- Peripheral Blood Stem Cell Transplantation
- Personalized Care
- Pertuzumab
- Pet-Ct Scan
- Pharmacokinetics
- Pharmacological Treatment Of Hypertension
- Portosystemic Shunt
- Pre-Operative Conditioning
- Radiomics
- Removal Of Central Venous Access Device
- Rilotumumab
- Rituximab
- Robotic Surgery
- Selpercatinib
- Single Photon Emission Computed Tomography
- Sintilimab
- Stem Cell Gene Editing
- Stem Cell Therapy
- Stereotactic Ablative Radiotherapy
- Stivarga
- Synthetic Lethality
- Tertiary Cancer Prevention
- Tocilizumab (ACTEMRA) Treatment
- Tofacitinib (XELJANZ) Treatment
- Total Proctocolectomy
- Translational Medicine Research
- Transplant Immunology
- Trastuzumab
- Trastuzumab Emtansine
- Tumor Marker Testing
- Ultrasound
- Vaccinations
- Vectibix
- Wellness Services
- Whole-Exome Sequencing
- Ziv-Aflibercept
Insurance
MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.
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List of insurance plans we accept
- First Health PPO
- Uniformed Services Family Health Plan
- DC/MD SHOP QHP Small Business Plans
- CIGNA EPO
- Priority Partners - Maryland Health Choice
- Options PPO Cardiac Global
- CareFirst Blue Choice Opt Out Plus Open Access (POS)
- Core Essential (HMO)
- Aetna Elect Choice/ EPO (Aetna Health Fund)
- IH-Open POS Plus
- Medicare Advantage - Advantra Value (PPO)
- Medicare FFS
- M.D. IPA Preferred (POS)
- United Student Resources
- Advantra Platinum (PPO)
- Private Fee-for-Service Plans (PFFS)
- Aetna Student Health Insurance
- IH-EPO Plus
- MultiPlan, Inc
- Choice Fund PPO
- CareFirst BlueCross BlueShield Advantage Core/Enhanced
- Healthy Blue (HMO, POS)
- CareFirst Dual Prime HMO-SNP
- Coventry of Delaware HMO/PPO
- Kaiser Permanente Select
- UHC Group Medicare Advantage Plans (HMO, POS, PPO)
- M.D. IPA (HMO)
- Aetna Medicare Advantage PFFS Plan
- Anthem BCBS of VA HealthKeepers (HMO)
- Optimum Choice
- Aetna Quality Point of Service (POS)
- CIGNA POS/Network POS
- MedStar Family Choice DC Healthcare Alliance
- Anthem BCBS of VA HealthKeepers Plus
- Aetna Premier 200PD
- CIGNA SureFit (HMO)
- Johns Hopkins Advantage MD HMO
- Kaiser Permanente HMO Plus and DHMO Plus Member
- Aetna HMO
- CareFirst Community Health Plan of MD
- Coventry Health Care of Virginia
- IH-Open POS II
- CareFirst FEP Blue Focus
- CareFirst Blue Card Program
- Coventry Health Care National Network PPO
- CIGNA HMO & Network (HMO)
- Kaiser Permanente Signature - Added Choice
- IH-Open Network Only Plus
- Aetna Traditional Choice (PPO)
- BlueChoice Open Access
- IH-Open EPO Plus
- AmeriHealth Caritas DC Healthy Families
- CareFirst Blue Preferred PPO
- UnitedHealthcare Individual Exchange Plans
- Geisinger Medicare Advantage
- Great-West Healthcare POS/CIGNA
- Optima Family Care MCO - VA Medicaid MCO
- Aetna Managed Choice (POS)
- MedStar Family Choice - Maryland Health Choice
- Amerigroup DC Alliance
- Aetna Elect Choice/ Open Access (POS)
- IH-PPO
- Humana Medicare Advantage - HMO Open Access
- Aetna Better Health of MD
- MedStar Family Choice DC Healthy Families
- IH-Network Only Plus
- Choice POS II
- United Healthcare Select HMO-EPO/NPP Cardiac Global
- Anthem BCBS Medi Blue Plus
- Police and Fire Clinic
- Aetna VA Exchange
- HUMANA/Choice Care Medicare Plans (Choice, Gold Choice)
- Employee Health Plan
- United Healthcare Choice Plus Cardiac Global
- Tricare Reserve Select
- CareFirst Maryland Point of Service Plan
- CareFirst Federal Employee Program (Std. & Basic PPO)
- Navigate
- Fee-for-Service (FFS) District of Columbia, Maryland and Virginia Medicaid
- MD IPA (HMO) & MD IPA Preferred Cardiac Global
- Cigna True Choice Medicare (PPO)
- United HealthCare Community Plan - Maryland Health Choice Program
- United Healthcare Navigate Cardiac Global
- IH-Open HMO Option
- CareFirst MedStar PPO
- Network OA
- CareFirst NASCO
- Anthem BCBS of VA HealthKeepers (POS & POS OA)
- Choice Care Network/HUMANA (PPO)
- Private Health Care Systems (PPO)
- United Healthcare Select HMO - EPO/NPP
- Aetna Basic
- WellPoint Maryland - Maryland Health Choice
- Anthem BCBS Medi Blue SNP
- Kaiser Permanente Flexible Choice POS Cardiac Global
- Lasso Healthcare - Medicare Medical Savings Account
- Erickson Advantage Plans
- Aetna HMO-Open Access/Select OA/HealthFund/Health Network Option OA
- Aetna Signature Administrator PPO/TPA
- CareFirst MedStar Select PPO
- Select HMO/HealthFund/Health Network
- BCBS Out-of-State Medicare Plans (Blue Advantage)
- Cigna Alliance Medicare (HMO)
- Kaiser Permanente Select - Added Choice
- Aetna Classic 5000PD
- Aetna Worker's Compensation Network
- Jai Medical Systems - Maryland Health Choice
- HighMark
- CareFirst BlueChoice HMO
- Kaiser Permanente Flexible Choice 3-tier POS
- TRICARE East Select
- Aetna Open Choice (PPO)
- First Health PPO
- Kaiser Permaenete Signature - Added Choice Cardiac Global
- OCI Direct (HMO)
- UnitedHealthcare Medicare Advantage DSNP District of Columbia
- Mamsi Life & Health (Indem./PPO) Cardiac Global
- Cigna Preferred Medicare (HMO)
- Cigna Achieve Medicare (HMO C-SNP)
- Aetna Advantage 5750
- CareFirst (NCA) Indemnity
- UnitedHealthcare and AARP Medicare Complete Plans
- CIGNA PPO Plus
- Aetna Advantage 6350PD
- Aetna Better Health of VA
- Sentara Health
- Anthem BCBS of VA Key Care POS/PPO/Indemnity
- CIGNA Connect EPO
- Kaiser Permanente Select Cardiac Global
- Aetna Medicare Advantage HMO & PPO Plans
- Anthem Federal Employee Program Standard
- Johns Hopkins Advantage MD PPO
- UHC Passport
- Medicare Direct
- United Healthcare Select Plus (POS)
- CIGNA Indemnity
- Humana Gold Plus HMO
- Maryland Physicians Care MCO
- Kaiser Maryland Medicaid MCO
- Veterans Affairs Community Care Network
- Magellan Complete Care of VA - VA Medicaid MCO
- NYC Medicare Advantage Plus
- Beech Street PPO
- Aetna Classic 3500
- CareFirst Administrators
- CareFirst Group Medicare Advantage prescription drug benefit (PPO)
- TRICARE East Prime
- IH-POS Plus
- CareFirst Group Medicare Advantage
- Humana Medicare Advantage - PPO
- HumanaChoice PPO
- Cigna True Choice Plus Medicare (PPO)
- CareFirst EPO
- United Healthcare Choice Cardiac Global
- United Healthcare Choice Plus
- IH-POS
- Optimum Choice Preferred (POS)
- IH-Open HMO
- IH-Indemnity
- HumanaChoice Honor's plan PPO
- HealthyBlue PPO
- Johns Hopkins Advantage MD PLUS PPO
- United Healthcare Choice
- Aetna Classic 5000
- Aetna Managed Choice Open Access (POS)
- Amerigroup DC Healthy Families
- Optimum Choice & Optimum Choice Preferred (POS) Cardiac Global
- CIGNA HMO Open Access
- Cigna TotalCare (HMO D-SNP)
- AmeriHealth Caritas DC Healthcare Alliance
- Kaiser Permanente Medicare Plus
- TriWest Healthcare Alliance
- Aetna Advantage 6350
- IH-HMO
- United Healthcare Community Plan - VA Medicaid MCO
- AMERIVANTAGE/Amerigroup Community Care
- CareFirst Blue Choice Opt Out Open Access
- OA Plus
- POS OA
- Kaiser Permanente Signature
- United Healthcare Options (PPO)
- Choice POS
- CareFirst Maryland Indemnity or PPO
- Blue Choice Advantage
- Alterwood Advanatge HMO & DSNP Plans
- United Medicare Private Fee-for-Service (PFFS) plans
- BCBS of Michigan (BCN Advantage,Security Blue, Freedom, Medicare PLUS Blue Group PPO)
- Anthem BCBS Medi Blue Dual Adv
- TRICARE for Life East
- Kaiser Permanente Medicare Advantage Signature and Select
- UnitedHealthcare Medicare Adv. Special Needs Plans
- Mamsi Life & Health (Indem./PPO)
- Anthem Federal Employee Program Basic
- CIGNA PPO
- Health Services for Children with Special Needs
- Choice POS II Open Access
Videos
Education
Board Certification: American Board of Internal Medicine, Internal Medicine
Fellowship: Tufts Medical Center (1984)
Fellowship: Tufts Medical Center (1982)
Residency: University of Vermont Medical Center (1981)
Internship: University of Vermont Medical Center (1978)
Medical School: Icahn School of Medicine at Mount Sinai (1977)
Awards
- Castle Connolly Top Doctors, 2021
- National Academy of Inventors Fellow, 2017-2018
- Recognition for Outstanding Contribution to Innovation and Commercialization, Georgetown University, Office of Technology, 2016
- Fellow, American College of Physicians, 2010
- America’s Top Oncologists, 2009
- America’s Top Doctors for Cancer, 2007 – Present
- Philadelphia Magazine's Top Docs, 2002; 2004 – 2007
- Who's Who in Medicine and Healthcare, 2002 - 2005
- G. Morris Dorrance, Jr. Endowed Chair in Medical Science, 2002
- American Association for Cancer Research Scientist-Survivor Program Award, 2002
- American Cancer Society - Southeast Region Scientific Research Award, 2002
- Janssen Pharmaceutical Research Foundation: Research Award for Outstanding Contributions to the Field of Receptor Targeted Therapy, 2001
- Best Doctors in America, 2000-2011
- National Cancer Institute Clinical Investigator Award, 1986
- American Cancer Society Career Development Award, 1985
Hospital affiliations
News and publications
- Georgetown Lombardi Comprehensive Cancer Center Receives Coveted ‘Comprehensive Cancer Center’ Status from National Cancer Institute
- Georgetown Lombardi Director Louis Weiner Receives AACR 2019 Distinguished Public Service Award
- Georgetown Lombardi’s Louis M. Weiner, MD, Named A National Academy of Inventors Fellow
- MedStar Health Collaborates with Inivata to Advance Precision Cancer Genomics Using Liquid Biopsy
- MedStar Health Taps Louis M. Weiner to Lead MedStar Georgetown Cancer Institute
- Enhancing Antibody Dependent Cellular Cytotoxicity (ADCC) as an Anti-Tumor Mechanism
- Manipulating Antibody Structure to Improve Selective Tumor Targeting
- Identifying Tumor Cell-Based Determinants of Antibody-Mediated Cell Killing
- Immunoconjugates for Cancer Therapy
- Antibody-initiated Cancer Immunotherapy
- Click here for a complete list of his research papers and scientific contributions.