Louis Marc Weiner, MD| Medical Oncology, Gastrointestinal Medical Oncology | MedStar Health
Louis Marc Weiner

Louis Marc Weiner, MD
Provider is directly employed by MedStar Health

4.8 out of 5 (117 reviews)

Specialties: Medical Oncology, Gastrointestinal Medical Oncology

Languages: English

202-444-1229

About me

Dr. Weiner is an internationally-recognized medical oncologist specializing in gastrointestinal cancers. He is also an accomplished researcher developing novel immunotherapy treatments – essentially triggering the body’s own immune system to identify and destroy cancer. He is recognized for his laboratory and clinical research focusing on these new therapeutic approaches. Dr. Weiner wants to understand why some tumors become resistant to therapy and other forms of cancer immunotherapy, with the goal of developing new treatments to overcome that resistance. He lectures extensively on these forms of targeted therapies, which block the growth and spread of cancer.

He serves as director of the Georgetown Lombardi Comprehensive Cancer Center – Washington, D.C.’s only National Cancer Institute-designated comprehensive cancer center – and the MedStar Georgetown Cancer Institute, which combines medical expertise, the latest therapies, and research across MedStar Health throughout the region. Dr. Weiner is also associate vice president at Georgetown University Medical Center, chair of the oncology department at Georgetown University School of Medicine, and clinical director of cancer services at MedStar Georgetown University Hospital.

In these roles, Dr. Weiner is responsible for operations, development, research, clinical and educational missions. As the Institute’s director, he oversees the clinical operations of the MedStar Health cancer service line, and leads the advancement of clinical care and research programs spanning prevention, treatment, rehabilitation, survivorship and end-of-life care across the region. With Georgetown Lombardi serving as the Institute’s “research engine,” patients throughout the region have access to unmatched expertise and clinical trials closer to where they live and work.

Dr. Weiner previously served as chairman of the Medical Oncology Department and vice president for Translational Research at Fox Chase Cancer Center in Philadelphia, PA. He held an endowed chair in medical science and was the driving force behind developing an immunotherapy laboratory and clinical programs, as well as establishing the Center's medical oncology fellowship program. Dr. Weiner also served as professor in the Department of Medicine at Temple University School of Medicine.

Dr. Weiner's Philosophy of Care
We live in a time of great hope in the area of cancer therapy. Many new, important and life-changing treatments are now being developed. We are privileged to offer patients tomorrow's treatments today. And now, through the MedStar Georgetown Cancer Institute, we can extend that mission across the region. With this progress in mind, I strive to offer all my patients the best possible therapies for their diseases, always mindful that I am neither treating a disease nor a patient, but a person with a life, a family and a combination of hopes and fears.

Working at a great cancer program like this gives me the opportunity to collaborate with leading international experts to assure that my patients can benefit from the best possible care during the course of their journeys.

Clinical areas of focus

  • Esophageal Cancer Treatment
  • Gastrointestinal Cancer Treatment
  • Liver Metastases Treatment
  • Low Anterior Resection
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Procedures I perform

  • A1c Testing
  • Adjuvant Hormone Therapy
  • Akt Inhibitors
  • Allergy
  • Anemia Management
  • Angiogenesis Inhibitors
  • Antiangiogenic Therapy
  • Aromatase Inhibitors
  • Arthrocentesis
  • Artificial Intelligence Therapy
  • Barium Enema
  • Bavituximab
  • Bioinformatics
  • Blinatumomab
  • Blood Banking
  • Brca Gene Testing
  • Cancer Biotechnology
  • Cancer Research Institute
  • Cancer Survivorship
  • Cancer Systems Biology
  • Cardiac Gene Expression
  • Chemoradiation
  • Chemotherapy Administration
  • Cholecystectomy
  • Cisplatin
  • Clinical Pathology
  • Clinical Trials
  • Coagulopathy Management
  • Cold Laser Therapy
  • Colectomy
  • Colorectal Cancer Treatment
  • Community Health
  • Comparative Effectiveness Research
  • Crispr-Cas9
  • Disease Prevention
  • Embolization For Bleeding
  • Endoscopic Mucosal Resection
  • Enteroscopy
  • Esophageal Cancer Treatment
  • Fertility Counseling
  • Gastrectomy
  • Gastrointestinal Cancer Treatment
  • Gemtuzumab Ozogamicin
  • Genomic Instability
  • Genomic Testing For Cancer
  • Growth Hormone Management With Octreotide
  • Health Outcomes Research
  • Helicobacter Pylori Stool Test
  • Hepatectomy
  • Hepatic Artery Infusion
  • Hepatoblastoma Treatment
  • Hormone Regulation With Leuprolide
  • Hormone Replacement Therapy
  • Ileal Pouch-Anal Anastomosis
  • Immunotherapy
  • Intravenous (IV) Fluids
  • Isolated Limb Perfusion
  • Laparoscopic Revision Of Gastric Restrictive Procedure
  • Lhrh Agonists
  • Liquid Biopsy
  • Liver Cancer Treatment
  • Liver Metastases Treatment
  • Low Anterior Resection
  • Lynch Syndrome Testing
  • Magnetic Resonance Imaging (MRI)
  • Minimally Invasive Surgery
  • Molecular Diagnostics
  • Nateglinide
  • Neoadjuvant Therapy
  • Neratinib
  • Nod-Like Receptor Monitoring
  • Pancreatectomy
  • Pancreatic Cancer Treatment
  • Pegargiminase
  • Pegilodecakin
  • Peginterferon Alfa-2A
  • Percutaneous Tumor Chemoembolization
  • Performance Improvement
  • Perianal Surgery
  • Peripheral Blood Stem Cell Transplantation
  • Personalized Care
  • Pertuzumab
  • Pet-Ct Scan
  • Pharmacokinetics
  • Pharmacological Treatment Of Hypertension
  • Portosystemic Shunt
  • Pre-Operative Conditioning
  • Radiomics
  • Removal Of Central Venous Access Device
  • Rilotumumab
  • Rituximab
  • Robotic Surgery
  • Selpercatinib
  • Single Photon Emission Computed Tomography
  • Sintilimab
  • Stem Cell Gene Editing
  • Stem Cell Therapy
  • Stereotactic Ablative Radiotherapy
  • Stivarga
  • Synthetic Lethality
  • Tertiary Cancer Prevention
  • Tocilizumab (ACTEMRA) Treatment
  • Tofacitinib (XELJANZ) Treatment
  • Total Proctocolectomy
  • Translational Medicine Research
  • Transplant Immunology
  • Trastuzumab
  • Trastuzumab Emtansine
  • Tumor Marker Testing
  • Ultrasound
  • Vaccinations
  • Vectibix
  • Wellness Services
  • Whole-Exome Sequencing
  • Ziv-Aflibercept
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Practice locations

Distance from Change LocationEnter your Location

3800 Reservoir Rd NW
Lombardi Cancer Center
Washington, DC, 20007

202-444-2223

Fax 202-444-1229

Get Directions

miles away

Fax 202-444-1229

Insurance

MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.

  • List of insurance plans we accept
    • Aetna Managed Choice Open Access (POS)
    • Humana Gold Plus HMO
    • UHC Group Medicare Advantage Plans (HMO, POS, PPO)
    • IH-HMO
    • Kaiser Maryland Medicaid MCO
    • Optimum Choice Preferred (POS)
    • CareFirst Federal Employee Program (Std. & Basic PPO)
    • MedStar Family Choice - Maryland Health Choice
    • Anthem BCBS Medi Blue SNP
    • CareFirst Community Health Plan of MD
    • Humana Medicare Advantage - HMO Open Access
    • IH-POS
    • IH-Open Network Only Plus
    • Anthem BCBS of VA HealthKeepers (HMO)
    • United Healthcare Select HMO-EPO/NPP Cardiac Global
    • Great-West Healthcare POS/CIGNA
    • Kaiser Permanente Flexible Choice POS Cardiac Global
    • Cigna True Choice Medicare (PPO)
    • Options PPO Cardiac Global
    • Medicare Direct
    • Medicare Advantage - Advantra Value (PPO)
    • CareFirst (NCA) Indemnity
    • Cigna True Choice Plus Medicare (PPO)
    • Police and Fire Clinic
    • BCBS of Michigan (BCN Advantage,Security Blue, Freedom, Medicare PLUS Blue Group PPO)
    • Kaiser Permanente Medicare Plus
    • Aetna Classic 3500
    • United Medicare Private Fee-for-Service (PFFS) plans
    • Kaiser Permanente Select - Added Choice
    • TRICARE East Prime
    • Mamsi Life & Health (Indem./PPO) Cardiac Global
    • Coventry of Delaware HMO/PPO
    • Choice Care Network/HUMANA (PPO)
    • Core Essential (HMO)
    • NYC Medicare Advantage Plus
    • Johns Hopkins Advantage MD PLUS PPO
    • OA Plus
    • United Healthcare Navigate Cardiac Global
    • Maryland Physicians Care MCO
    • Aetna Student Health Insurance
    • Aetna Better Health of VA
    • Anthem BCBS Medi Blue Dual Adv
    • First Health PPO
    • IH-Open POS II
    • Johns Hopkins Advantage MD PPO
    • CareFirst FEP Blue Focus
    • Private Fee-for-Service Plans (PFFS)
    • Aetna Open Choice (PPO)
    • CareFirst Blue Card Program
    • Anthem BCBS Medi Blue Plus
    • Mamsi Life & Health (Indem./PPO)
    • HUMANA/Choice Care Medicare Plans (Choice, Gold Choice)
    • Kaiser Permanente Medicare Advantage Signature and Select
    • United Healthcare Choice Plus Cardiac Global
    • Aetna HMO
    • Anthem Federal Employee Program Standard
    • Aetna Elect Choice/ EPO (Aetna Health Fund)
    • IH-Open POS Plus
    • Amerigroup DC Alliance
    • CareFirst BlueChoice HMO
    • M.D. IPA (HMO)
    • IH-Open EPO Plus
    • CareFirst EPO
    • Tricare Reserve Select
    • Fee-for-Service (FFS) District of Columbia, Maryland and Virginia Medicaid
    • Aetna Traditional Choice (PPO)
    • IH-EPO Plus
    • CareFirst Blue Choice Opt Out Open Access
    • Cigna TotalCare (HMO D-SNP)
    • CIGNA EPO
    • Optima Family Care MCO - VA Medicaid MCO
    • CareFirst Blue Preferred PPO
    • CareFirst NASCO
    • Cigna Alliance Medicare (HMO)
    • United Healthcare Choice Cardiac Global
    • CareFirst Maryland Indemnity or PPO
    • Network OA
    • IH-Network Only Plus
    • Uniformed Services Family Health Plan
    • Anthem Federal Employee Program Basic
    • Kaiser Permanente Select Cardiac Global
    • Aetna Managed Choice (POS)
    • United Healthcare Options (PPO)
    • UnitedHealthcare Individual Exchange Plans
    • CareFirst Dual Prime HMO-SNP
    • CIGNA HMO Open Access
    • Choice Fund PPO
    • Optimum Choice & Optimum Choice Preferred (POS) Cardiac Global
    • CareFirst Maryland Point of Service Plan
    • CareFirst MedStar Select PPO
    • United Healthcare Choice
    • Healthy Blue (HMO, POS)
    • OCI Direct (HMO)
    • Aetna HMO-Open Access/Select OA/HealthFund/Health Network Option OA
    • Geisinger Medicare Advantage
    • Kaiser Permanente Select
    • United Healthcare Choice Plus
    • Aetna VA Exchange
    • United HealthCare Community Plan - Maryland Health Choice Program
    • CareFirst BlueCross BlueShield Advantage Core/Enhanced
    • HealthyBlue PPO
    • IH-PPO
    • Advantra Platinum (PPO)
    • CareFirst Group Medicare Advantage prescription drug benefit (PPO)
    • First Health PPO
    • CIGNA PPO
    • Humana Medicare Advantage - PPO
    • UnitedHealthcare Medicare Adv. Special Needs Plans
    • Choice POS
    • Choice POS II
    • Aetna Advantage 6350PD
    • IH-Open HMO Option
    • Coventry Health Care of Virginia
    • CIGNA PPO Plus
    • Johns Hopkins Advantage MD HMO
    • United Healthcare Community Plan - VA Medicaid MCO
    • United Healthcare Select HMO - EPO/NPP
    • TriWest Healthcare Alliance
    • IH-POS Plus
    • CareFirst Blue Choice Opt Out Plus Open Access (POS)
    • POS OA
    • United Healthcare Select Plus (POS)
    • Aetna Elect Choice/ Open Access (POS)
    • Anthem BCBS of VA HealthKeepers (POS & POS OA)
    • CareFirst Group Medicare Advantage
    • CIGNA Connect EPO
    • AMERIVANTAGE/Amerigroup Community Care
    • Jai Medical Systems - Maryland Health Choice
    • BlueChoice Open Access
    • Employee Health Plan
    • CIGNA POS/Network POS
    • UnitedHealthcare Medicare Advantage DSNP District of Columbia
    • UnitedHealthcare and AARP Medicare Complete Plans
    • Alterwood Advanatge HMO & DSNP Plans
    • Optimum Choice
    • Medicare FFS
    • Aetna Signature Administrator PPO/TPA
    • Aetna Advantage 5750
    • MD IPA (HMO) & MD IPA Preferred Cardiac Global
    • M.D. IPA Preferred (POS)
    • Health Services for Children with Special Needs
    • Lasso Healthcare - Medicare Medical Savings Account
    • Erickson Advantage Plans
    • Choice POS II Open Access
    • MultiPlan, Inc
    • Aetna Basic
    • WellPoint Maryland - Maryland Health Choice
    • CIGNA Indemnity
    • Amerigroup DC Healthy Families
    • AmeriHealth Caritas DC Healthcare Alliance
    • Anthem BCBS of VA Key Care POS/PPO/Indemnity
    • Kaiser Permaenete Signature - Added Choice Cardiac Global
    • Cigna Preferred Medicare (HMO)
    • Aetna Premier 200PD
    • IH-Open HMO
    • Aetna Medicare Advantage PFFS Plan
    • Kaiser Permanente Flexible Choice 3-tier POS
    • Aetna Classic 5000PD
    • Select HMO/HealthFund/Health Network
    • Aetna Better Health of MD
    • Sentara Health
    • Private Health Care Systems (PPO)
    • CIGNA HMO & Network (HMO)
    • MedStar Family Choice DC Healthy Families
    • United Student Resources
    • Aetna Classic 5000
    • TRICARE East Select
    • Cigna Achieve Medicare (HMO C-SNP)
    • TRICARE for Life East
    • Aetna Quality Point of Service (POS)
    • Aetna Medicare Advantage HMO & PPO Plans
    • IH-Indemnity
    • Priority Partners - Maryland Health Choice
    • BCBS Out-of-State Medicare Plans (Blue Advantage)
    • Beech Street PPO
    • Kaiser Permanente Signature
    • CareFirst Administrators
    • Kaiser Permanente Signature - Added Choice
    • Anthem BCBS of VA HealthKeepers Plus
    • Navigate
    • HumanaChoice PPO
    • Aetna Worker's Compensation Network
    • MedStar Family Choice DC Healthcare Alliance
    • Coventry Health Care National Network PPO
    • CareFirst MedStar PPO
    • HighMark
    • HumanaChoice Honor's plan PPO
    • UHC Passport
    • CIGNA SureFit (HMO)
    • DC/MD SHOP QHP Small Business Plans
    • Veterans Affairs Community Care Network
    • Blue Choice Advantage
    • Magellan Complete Care of VA - VA Medicaid MCO
    • Kaiser Permanente HMO Plus and DHMO Plus Member
    • Aetna Advantage 6350
    • AmeriHealth Caritas DC Healthy Families

Videos

Education

Board Certification: American Board of Internal Medicine, Medical Oncology

Fellowship: Tufts Medical Center (1984)

Fellowship: Tufts Medical Center (1982)

Residency: University of Vermont Medical Center (1981)

Internship: University of Vermont Medical Center (1978)

Medical School: Icahn School of Medicine at Mount Sinai (1977)

Awards

  • Castle Connolly Top Doctors, 2021
  • National Academy of Inventors Fellow, 2017-2018
  • Recognition for Outstanding Contribution to Innovation and Commercialization, Georgetown University, Office of Technology, 2016
  • Fellow, American College of Physicians, 2010
  • America’s Top Oncologists, 2009               
  • America’s Top Doctors for Cancer, 2007 – Present
  • Philadelphia Magazine's Top Docs, 2002; 2004 – 2007
  • Who's Who in Medicine and Healthcare, 2002 - 2005
  • G. Morris Dorrance, Jr. Endowed Chair in Medical Science, 2002
  • American Association for Cancer Research Scientist-Survivor Program Award, 2002
  • American Cancer Society - Southeast Region Scientific Research Award, 2002
  • Janssen Pharmaceutical Research Foundation: Research Award for Outstanding Contributions to the Field of Receptor Targeted Therapy, 2001
  • Best Doctors in America, 2000-2011
  • National Cancer Institute Clinical Investigator Award, 1986
  • American Cancer Society Career Development Award, 1985

News and publications

Dr. Weiner has authored more than 200 publications throughout his career centering on the following core topics:
  • Enhancing Antibody Dependent Cellular Cytotoxicity (ADCC) as an Anti-Tumor Mechanism
  • Manipulating Antibody Structure to Improve Selective Tumor Targeting
  • Identifying Tumor Cell-Based Determinants of Antibody-Mediated Cell Killing
  • Immunoconjugates for Cancer Therapy
  • Antibody-initiated Cancer Immunotherapy
  • Click here for a complete list of his research papers and scientific contributions. 

Ratings and reviews

  • Explanations the care provider gave you about your problem or condition

    4.8
  • Extent to which the care provider listened to you

    4.8
  • Care provider’s discussion of any proposed treatment (options, risks, benefits, etc.)

    4.8
  • Provider included you in decisions

    4.8
  • Concern the care provider showed for your questions or worries

    4.8
  • Likelihood of recommending this care provider to others

    4.8
  • Jan 28, 2025

    Dr. Weiner is amazing. So knowledgeable and great people skills I am very luck to be under his care.

  • Nov 14, 2024

    Great!

  • Mar 21, 2024

    The best!