Louis Marc Weiner, MD| Gastrointestinal Medical Oncology, Medical Oncology | MedStar Health
Louis Marc Weiner

Louis Marc Weiner, MD
Provider is directly employed by MedStar Health

4.8 out of 5 (116 reviews)

Specialties: Gastrointestinal Medical Oncology, Medical Oncology

Languages: English

202-444-1229

About me

Dr. Weiner is an internationally-recognized medical oncologist specializing in gastrointestinal cancers. He is also an accomplished researcher developing novel immunotherapy treatments – essentially triggering the body’s own immune system to identify and destroy cancer. He is recognized for his laboratory and clinical research focusing on these new therapeutic approaches. Dr. Weiner wants to understand why some tumors become resistant to therapy and other forms of cancer immunotherapy, with the goal of developing new treatments to overcome that resistance. He lectures extensively on these forms of targeted therapies, which block the growth and spread of cancer.

He serves as director of the Georgetown Lombardi Comprehensive Cancer Center – Washington, D.C.’s only National Cancer Institute-designated comprehensive cancer center – and the MedStar Georgetown Cancer Institute, which combines medical expertise, the latest therapies, and research across MedStar Health throughout the region. Dr. Weiner is also associate vice president at Georgetown University Medical Center, chair of the oncology department at Georgetown University School of Medicine, and clinical director of cancer services at MedStar Georgetown University Hospital.

In these roles, Dr. Weiner is responsible for operations, development, research, clinical and educational missions. As the Institute’s director, he oversees the clinical operations of the MedStar Health cancer service line, and leads the advancement of clinical care and research programs spanning prevention, treatment, rehabilitation, survivorship and end-of-life care across the region. With Georgetown Lombardi serving as the Institute’s “research engine,” patients throughout the region have access to unmatched expertise and clinical trials closer to where they live and work.

Dr. Weiner previously served as chairman of the Medical Oncology Department and vice president for Translational Research at Fox Chase Cancer Center in Philadelphia, PA. He held an endowed chair in medical science and was the driving force behind developing an immunotherapy laboratory and clinical programs, as well as establishing the Center's medical oncology fellowship program. Dr. Weiner also served as professor in the Department of Medicine at Temple University School of Medicine.

Dr. Weiner's Philosophy of Care
We live in a time of great hope in the area of cancer therapy. Many new, important and life-changing treatments are now being developed. We are privileged to offer patients tomorrow's treatments today. And now, through the MedStar Georgetown Cancer Institute, we can extend that mission across the region. With this progress in mind, I strive to offer all my patients the best possible therapies for their diseases, always mindful that I am neither treating a disease nor a patient, but a person with a life, a family and a combination of hopes and fears.

Working at a great cancer program like this gives me the opportunity to collaborate with leading international experts to assure that my patients can benefit from the best possible care during the course of their journeys.

Clinical areas of focus

  • Abdominal Wall Tumor Resection
  • Esophageal Cancer Treatment
  • Gastric Cancer
  • Gastrointestinal Cancer Treatment
  • Liver Metastases Treatment
  • Low Anterior Resection
  • Rectal Cancer
  • Small Intestine Cancer
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Conditions and procedures

Conditions I treat

  • Abnormal Tumor Markers
  • Anal Cancer
  • Appendiceal Cancer
  • Benign Neoplasm Of Kidney
  • Bile Duct Cancer
  • Bladder Carcinoma
  • Cancer Of The Appendix
  • Chronic Eosinophilic Leukemia
  • Colon Cancer
  • Colorectal Malignancy
  • Diseases Of The Small Intestine
  • Duodenal Cancer
  • Esophageal Adenocarcinoma
  • Esophageal Cancer
  • Esophagus Cancer
  • Family History Of Malignant Neoplasm
  • Gallbladder Cancer
  • Gastric Adenocarcinoma
  • Gastric Cancer
  • Gastrointestinal Stromal Tumor (GIST)
  • Gastrointestinal Stromal Tumors (GIST)
  • Hepatoblastoma
  • Immunoproliferative Diseases
  • Intrahepatic Bile Ducts Cancer
  • Liver Cancer
  • Liver Metastases
  • Malignant Immunoproliferative Diseases And B
  • Malignant Neoplasm
  • Malignant Neoplasm Of Connective And Soft Tissue
  • Malignant Neoplasm Of Lymph Nodes
  • Malignant Neoplasm Of Retroperitoneum
  • Malignant Neuroendocrine Tumors
  • Neoplasm Analysis
  • Pancreas Cancer
  • Pancreatic Adenocarcinoma
  • Pancreatic Neuroendocrine Tumor (PNET)
  • Rectal Adenocarcinoma
  • Rectal Cancer
  • Secondary Liver Cancer
  • Small Intestine Cancer
  • Squamous Cell Carcinoma Of The Esophagus
  • Stomach Cancer
  • Stomatitis And Related Lesions
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Procedures I perform

  • A1c Testing
  • Abdominal Wall Tumor Resection
  • Adjuvant Hormone Therapy
  • Akt Inhibitors
  • Allergy
  • Anemia Management
  • Angiogenesis Inhibitors
  • Antiangiogenic Therapy
  • Aromatase Inhibitors
  • Arthrocentesis
  • Artificial Intelligence Therapy
  • Barium Enema
  • Bavituximab
  • Bioinformatics
  • Blinatumomab
  • Blood Banking
  • Brca Gene Testing
  • Cancer Biotechnology
  • Cancer Research Institute
  • Cancer Survivorship
  • Cancer Systems Biology
  • Cardiac Cell Therapy
  • Cardiac Gene Expression
  • Chemoradiation
  • Chemotherapy Administration
  • Cholecystectomy
  • Cisplatin
  • Clinical Pathology
  • Clinical Trials
  • Coagulopathy Management
  • Cold Laser Therapy
  • Colectomy
  • Colorectal Cancer Treatment
  • Community Health
  • Comparative Effectiveness Research
  • Computerized Tomography (CT) Scan
  • Crispr-Cas9
  • Disease Prevention
  • Embolization For Bleeding
  • Endoscopic Mucosal Resection
  • Enteroscopy
  • Esophageal Cancer Treatment
  • Fertility Counseling
  • Gastrectomy
  • Gastrointestinal Cancer Treatment
  • Gemtuzumab Ozogamicin
  • Genomic Instability
  • Genomic Testing For Cancer
  • Growth Hormone Management With Octreotide
  • Health Outcomes Research
  • Helicobacter Pylori Stool Test
  • Hepatectomy
  • Hepatic Artery Infusion
  • Hepatoblastoma Treatment
  • Hormone Regulation With Leuprolide
  • Hormone Replacement Therapy
  • I-131 Therapy
  • Ileal Pouch-Anal Anastomosis
  • Immunotherapy
  • Inpatient Palliative Care
  • Internal Jugular Central Line Placement
  • Internal Radiation Therapy
  • Intra-Arterial Infusion Of Chemotherapy
  • Intravenous (IV) Fluids
  • Isolated Limb Perfusion
  • Laparoscopic Revision Of Gastric Restrictive Procedure
  • Lhrh Agonists
  • Liquid Biopsy
  • Liver Cancer Treatment
  • Liver Metastases Treatment
  • Low Anterior Resection
  • Lynch Syndrome Testing
  • Magnetic Resonance Imaging (MRI)
  • Methylation Profiling
  • Minimally Invasive Surgery
  • Molecular Diagnostics
  • Muscle Injection
  • Nateglinide
  • Neoadjuvant Therapy
  • Neratinib
  • Nod-Like Receptor Monitoring
  • Nutrition Counseling
  • Pain Medication Management
  • Pancreatectomy
  • Pancreatic Cancer Treatment
  • Parotid Biopsy
  • Pegargiminase
  • Pegilodecakin
  • Peginterferon Alfa-2A
  • Percutaneous Tumor Chemoembolization
  • Performance Improvement
  • Perianal Surgery
  • Peripheral Blood Stem Cell Transplantation
  • Personalized Care
  • Pertuzumab
  • Pet-Ct Scan
  • Pharmacokinetics
  • Pharmacological Treatment Of Hypertension
  • Portosystemic Shunt
  • Pre-Operative Conditioning
  • Radiation Therapy
  • Radiomics
  • Removal Of Central Venous Access Device
  • Rilotumumab
  • Rituximab
  • Robotic Surgery
  • Selpercatinib
  • Single Photon Emission Computed Tomography
  • Sintilimab
  • Stem Cell Gene Editing
  • Stem Cell Therapy
  • Stereotactic Ablative Radiotherapy
  • Stivarga
  • Synthetic Lethality
  • Tertiary Cancer Prevention
  • Tocilizumab (ACTEMRA) Treatment
  • Tofacitinib (XELJANZ) Treatment
  • Total Proctocolectomy
  • Translational Medicine Research
  • Transplant Immunology
  • Trastuzumab
  • Trastuzumab Emtansine
  • Tumor Biopsy
  • Tumor Marker Testing
  • Ultrasound
  • Vaccinations
  • Vectibix
  • Venous Access Device Irrigation
  • Wellness Services
  • Whole-Exome Sequencing
  • Ziv-Aflibercept
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Practice locations

Distance from Change LocationEnter your Location

3800 Reservoir Rd NW
Lombardi Cancer Center
Washington, DC, 20007

202-444-2223

Fax 202-444-1229

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miles away

Fax 202-444-1229

Insurance

MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.

  • List of insurance plans we accept
    • CareFirst Maryland Indemnity or PPO
    • Aetna HMO-Open Access/Select OA/HealthFund/Health Network Option OA
    • Cigna Achieve Medicare (HMO C-SNP)
    • Aetna Classic 3500
    • United Healthcare Select HMO - EPO/NPP
    • Aetna Traditional Choice (PPO)
    • Anthem BCBS of VA HealthKeepers Plus
    • Mamsi Life & Health (Indem./PPO)
    • UnitedHealthcare Medicare Advantage DSNP District of Columbia
    • Optimum Choice Preferred (POS)
    • Anthem BCBS Medi Blue Dual Adv
    • MedStar Family Choice DC Healthcare Alliance
    • CareFirst BlueCross BlueShield Advantage Core/Enhanced
    • HUMANA/Choice Care Medicare Plans (Choice, Gold Choice)
    • Cigna True Choice Plus Medicare (PPO)
    • Anthem BCBS of VA HealthKeepers (HMO)
    • UnitedHealthcare and AARP Medicare Complete Plans
    • Aetna Better Health of VA
    • Network OA
    • Coventry Health Care of Virginia
    • IH-Open POS Plus
    • AmeriHealth Caritas DC Healthcare Alliance
    • United Healthcare Select HMO-EPO/NPP Cardiac Global
    • Maryland Physicians Care MCO
    • Private Fee-for-Service Plans (PFFS)
    • Fee-for-Service (FFS) District of Columbia, Maryland and Virginia Medicaid
    • Uniformed Services Family Health Plan
    • MedStar Family Choice - Maryland Health Choice
    • Healthy Blue (HMO, POS)
    • CIGNA PPO
    • Kaiser Permanente Signature - Added Choice
    • Choice POS II
    • Anthem BCBS Medi Blue SNP
    • CIGNA Connect EPO
    • Aetna Basic
    • IH-Open Network Only Plus
    • AMERIVANTAGE/Amerigroup Community Care
    • POS OA
    • Johns Hopkins Advantage MD PLUS PPO
    • Mamsi Life & Health (Indem./PPO)
    • IH-EPO Plus
    • CIGNA EPO
    • HumanaChoice Honor's plan PPO
    • CareFirst Blue Card Program
    • Great-West Healthcare POS/CIGNA
    • IH-POS
    • Aetna Premier 200PD
    • Kaiser Permanente Medicare Plus
    • Options PPO Cardiac Global
    • Aetna Signature Administrator PPO/TPA
    • Core Essential (HMO)
    • Mamsi Life & Health (Indem./PPO) Cardiac Global
    • IH-Open EPO Plus
    • Aetna VA Exchange
    • Aetna Advantage 6350PD
    • Kaiser Permanente Signature
    • Coventry Health Care National Network PPO
    • CIGNA SureFit (HMO)
    • Kaiser Permanente Select
    • IH-Open HMO Option
    • Medicare Advantage - Advantra Value (PPO)
    • MedStar Family Choice DC Healthy Families
    • Medicare Direct
    • Choice Care Network/HUMANA (PPO)
    • Aetna Elect Choice/ EPO (Aetna Health Fund)
    • Kaiser Permanente Flexible Choice 3-tier POS
    • MedStar Family Choice DC Healthcare Alliance
    • Aetna Advantage 5750
    • IH-Network Only Plus
    • Coventry of Delaware HMO/PPO
    • MedStar Family Choice - Maryland Health Choice
    • United Healthcare Choice Plus Cardiac Global
    • BlueChoice Open Access
    • UnitedHealthcare Individual Exchange Plans
    • Tricare Reserve Select
    • CareFirst MedStar Select PPO
    • Private Health Care Systems (PPO)
    • Beech Street PPO
    • Lasso Healthcare - Medicare Medical Savings Account
    • CareFirst Group Medicare Advantage prescription drug benefit (PPO)
    • TriWest Healthcare Alliance
    • Aetna Open Choice (PPO)
    • United Healthcare Community Plan - VA Medicaid MCO
    • CareFirst BlueChoice HMO
    • CareFirst Blue Choice Opt Out Plus Open Access (POS)
    • CareFirst NASCO
    • CareFirst EPO
    • CIGNA Indemnity
    • CareFirst FEP Blue Focus
    • Johns Hopkins Advantage MD PPO
    • IH-Open HMO
    • Jai Medical Systems - Maryland Health Choice
    • Amerigroup DC Alliance
    • WellPoint Maryland - Maryland Health Choice
    • Optima Family Care MCO - VA Medicaid MCO
    • Anthem BCBS of VA Key Care POS/PPO/Indemnity
    • Aetna Quality Point of Service (POS)
    • Aetna Medicare Advantage PFFS Plan
    • Cigna Alliance Medicare (HMO)
    • Cigna TotalCare (HMO D-SNP)
    • CareFirst Dual Prime HMO-SNP
    • MD IPA (HMO) & MD IPA Preferred Cardiac Global
    • Geisinger Medicare Advantage
    • HumanaChoice PPO
    • M.D. IPA Preferred (POS)
    • CareFirst Maryland Point of Service Plan
    • Kaiser Maryland Medicaid MCO
    • UnitedHealthcare Individual Exchange Plans
    • TRICARE East Prime
    • Choice Fund PPO
    • CareFirst Community Health Plan of MD
    • CareFirst Blue Choice Opt Out Open Access
    • UnitedHealthcare Medicare Adv. Special Needs Plans
    • Fee-for-Service (FFS) District of Columbia, Maryland and Virginia Medicaid
    • Magellan Complete Care of VA - VA Medicaid MCO
    • Aetna Managed Choice (POS)
    • Aetna Medicare Advantage HMO & PPO Plans
    • Cigna True Choice Medicare (PPO)
    • IH-POS Plus
    • HighMark
    • Veterans Affairs Community Care Network
    • Advantra Platinum (PPO)
    • CareFirst Administrators
    • Kaiser Permanente Select Cardiac Global
    • Police and Fire Clinic
    • Priority Partners - Maryland Health Choice
    • BCBS Out-of-State Medicare Plans (Blue Advantage)
    • Humana Gold Plus HMO
    • CareFirst Blue Preferred PPO
    • Aetna Student Health Insurance
    • Anthem BCBS of VA HealthKeepers (POS & POS OA)
    • CIGNA HMO Open Access
    • United Healthcare Select Plus (POS)
    • United Healthcare Navigate Cardiac Global
    • Navigate
    • Optimum Choice & Optimum Choice Preferred (POS) Cardiac Global
    • CIGNA PPO Plus
    • Anthem BCBS Medi Blue Plus
    • OA Plus
    • United Student Resources
    • Aetna Elect Choice/ Open Access (POS)
    • Employee Health Plan
    • United Healthcare Choice Plus
    • Amerigroup DC Healthy Families
    • Anthem Federal Employee Program Basic
    • First Health PPO
    • Aetna Classic 5000
    • Aetna HMO
    • M.D. IPA (HMO)
    • OCI Direct (HMO)
    • AmeriHealth Caritas DC Healthy Families
    • Blue Choice Advantage
    • UHC Group Medicare Advantage Plans (HMO, POS, PPO)
    • Kaiser Permanente Flexible Choice POS Cardiac Global
    • Kaiser Permanente Medicare Advantage Signature and Select
    • UHC Passport
    • Cigna Preferred Medicare (HMO)
    • Select HMO/HealthFund/Health Network
    • MultiPlan, Inc
    • United Medicare Private Fee-for-Service (PFFS) plans
    • Aetna Worker's Compensation Network
    • DC/MD SHOP QHP Small Business Plans
    • CareFirst Group Medicare Advantage
    • CIGNA HMO & Network (HMO)
    • Aetna Managed Choice Open Access (POS)
    • United Healthcare Choice Cardiac Global
    • First Health PPO
    • Optimum Choice
    • United HealthCare Community Plan - Maryland Health Choice Program
    • CareFirst (NCA) Indemnity
    • TRICARE for Life East
    • United Healthcare Choice
    • Aetna Classic 5000PD
    • IH-Open POS II
    • Kaiser Permanente HMO Plus and DHMO Plus Member
    • IH-HMO
    • CareFirst Federal Employee Program (Std. & Basic PPO)
    • CIGNA POS/Network POS
    • Johns Hopkins Advantage MD HMO
    • BCBS of Michigan (BCN Advantage,Security Blue, Freedom, Medicare PLUS Blue Group PPO)
    • NYC Medicare Advantage Plus
    • Kaiser Permanente Select - Added Choice
    • Alterwood Advanatge HMO & DSNP Plans
    • IH-Indemnity
    • Humana Medicare Advantage - PPO
    • Humana Medicare Advantage - HMO Open Access
    • Medicare FFS
    • Choice POS II Open Access
    • Erickson Advantage Plans
    • Kaiser Permaenete Signature - Added Choice Cardiac Global
    • United Healthcare Options (PPO)
    • Aetna Better Health of MD
    • IH-PPO
    • CareFirst MedStar PPO
    • HealthyBlue PPO
    • Sentara Health
    • TRICARE East Select
    • Aetna Advantage 6350
    • Anthem Federal Employee Program Standard
    • Choice POS
    • Health Services for Children with Special Needs

Videos

Education

Board Certification: American Board of Internal Medicine, Medical Oncology

Fellowship: Tufts Medical Center (1984)

Fellowship: Tufts Medical Center (1982)

Residency: University of Vermont Medical Center (1981)

Internship: University of Vermont Medical Center (1978)

Medical School: Icahn School of Medicine at Mount Sinai (1977)

Awards

  • Castle Connolly Top Doctors, 2021
  • National Academy of Inventors Fellow, 2017-2018
  • Recognition for Outstanding Contribution to Innovation and Commercialization, Georgetown University, Office of Technology, 2016
  • Fellow, American College of Physicians, 2010
  • America’s Top Oncologists, 2009               
  • America’s Top Doctors for Cancer, 2007 – Present
  • Philadelphia Magazine's Top Docs, 2002; 2004 – 2007
  • Who's Who in Medicine and Healthcare, 2002 - 2005
  • G. Morris Dorrance, Jr. Endowed Chair in Medical Science, 2002
  • American Association for Cancer Research Scientist-Survivor Program Award, 2002
  • American Cancer Society - Southeast Region Scientific Research Award, 2002
  • Janssen Pharmaceutical Research Foundation: Research Award for Outstanding Contributions to the Field of Receptor Targeted Therapy, 2001
  • Best Doctors in America, 2000-2011
  • National Cancer Institute Clinical Investigator Award, 1986
  • American Cancer Society Career Development Award, 1985

News and publications

Dr. Weiner has authored more than 200 publications throughout his career centering on the following core topics:
  • Enhancing Antibody Dependent Cellular Cytotoxicity (ADCC) as an Anti-Tumor Mechanism
  • Manipulating Antibody Structure to Improve Selective Tumor Targeting
  • Identifying Tumor Cell-Based Determinants of Antibody-Mediated Cell Killing
  • Immunoconjugates for Cancer Therapy
  • Antibody-initiated Cancer Immunotherapy
  • Click here for a complete list of his research papers and scientific contributions. 

Ratings and reviews

  • Explanations the care provider gave you about your problem or condition

    4.8
  • Extent to which the care provider listened to you

    4.8
  • Care provider’s discussion of any proposed treatment (options, risks, benefits, etc.)

    4.8
  • Provider included you in decisions

    4.8
  • Concern the care provider showed for your questions or worries

    4.8
  • Likelihood of recommending this care provider to others

    4.8
  • Jan 28, 2025

    Dr. Weiner is amazing. So knowledgeable and great people skills I am very luck to be under his care.

  • Nov 14, 2024

    Great!

  • Mar 21, 2024

    The best!