Hector M. Garcia-Garcia

Hector M. Garcia-Garcia, MD, PhDHector M. Garcia-Garcia, MD, PhD, is director of angiographic, intravascular ultrasound, optical coherence tomography and near infrared spectroscopy imaging at the Cardiovascular Core Laboratory, MedStar Cardiovascular Research Network, MedStar Washington Hospital Center (MWHC). In addition, he is chairman of the Clinical Event committee and an attending cardiologist at MedStar Heart and Vascular Institute, MWHC.

Dr. Garcia-Garcia is skilled in using a variety of intravascular imaging techniques for diagnostic and interventional purposes. In his clinical work, he diagnoses and treats patients for cardiovascular conditions, such as atherosclerosis, hyperlipidemia, and myocardial infarction.

As an expert in innovative invasive and non-invasive cardiovascular technologies, as well as an accomplished researcher, Dr. Garcia-Garcia has been published in many international medical journals. His research on topics including ST-elevation myocardial infarction, revascularization with percutaneous coronary intervention using novel bioresorbable scaffolds, and intravascular imaging (e.g., intravascular ultrasound, virtual histology, echogenicity, optical coherence tomography, and light intensity analysis) has appeared in the Lancet, the Journal of the American Medical Association (JAMA), the Journal of the American College of Cardiology (JACC), Circulation,  EuroIntervention, and other prominent medical journals. He has authored or co-authored more than 350 peer-reviewed publications, and he has written numerous chapters published in cardiovascular textbooks. He currently serves as an editorial consultant for JACC Cardiovascular Imaging.

Dr. Garcia-Garcia is a fellow of several professional societies, including the European Society of Cardiology and the American College of Cardiology. Fluent in English, Spanish, and Dutch, he frequently presents his research to cardiology professionals worldwide. Prior to joining MedStar, he served as director of the core invasive imaging laboratory at a clinical research organization and as a researcher at the Erasmus Medical Center, Rotterdam.

His medical degree is from the Universidad Autónoma de Guadalajara, Guadalajara, Mexico. He completed a residency in cardiology and a fellowship in interventional cardiology at the Instituto Nacional de Cardiologia Ignacio Chavez and the Universidad Nacional Autónoma de Mexico. His master’s degree in epidemiology and his doctorate degree in clinical research are from the Erasmus University Rotterdam, Netherlands.

Research Interests

Dr. Garcia-Garcia’s research interests include the following:

  • Imaging techniques for assessing coronary atherosclerosis (e.g., optical coherence tomography and intravascular ultrasound)
  • Treatment of coronary stenosis with bioresorbable scaffolds
  • Treatment of coronary stenosis with novel pharmacological agents

Selected Research

Methods of assessing bioresorbable coronary devices

In this research, Dr. Garcia-Garcia and colleagues provide an overview of the existing methods for assessing bioresorbable devices, from noninvasive to invasive, from light- to sound-based, and with morphological to functional parameters. This research was published in JACC Cardiovascular Imaging (2014;7:1130-48. doi: 10.1016/j.jcmg.2014.06.018).

Prognostic determinants of coronary atherosclerosis in stable ischemic heart disease

In this research, Dr. Garcia-Garcia and colleagues reviewed the anatomic, physiologic, and morphologic determinants of coronary atherosclerosis in patients with stable ischemic heart disease and explored algorithms that may enable practical diagnostic and therapeutic strategies. This research was published in Circulation Research (2016;119:317-29. doi: 10.1161/CIRCRESAHA.116.308952).

Comparison of heparin, bivalirudin, and different glycoprotein IIb/IIIa inhibitor regimens for anticoagulation during percutaneous coronary intervention

In this Bayesian network meta-analysis of 38,645 patients, Dr. Garcia-Garcia and colleagues compared the use of different glycoprotein IIb/IIIa inhibitor strategies with heparin and bivalirudin for percutaneous coronary intervention. This study was published in Cardiovascular Revascularization Medicine (2016, doi: 10.1016/j.carrev.2016.09.011).

Integrated Biomarker and Imaging Study 3 (IBIS-3)

In this study to assess the ability of rosuvastatin to decrease necrotic core in coronary arteries, Dr. Garcia-Garcia and colleagues evaluated the treatment effects of high-intensity statin therapy on compositional coronary plaque changes. This study was published in EuroIntervention (2016;12:734-9. doi: 10.4244/EIJV12I6A118).

Safety and effectiveness of a second-generation drug-eluting absorbable metal scaffold in patients with de-novo coronary artery lesions (BIOSOLVE-II)

In this multi-center first-in-humans study, Dr. Garcia-Garcia and colleagues assessed the safety and effectiveness of a second generation drug-eluting absorbable magnesium scaffold in patients with de-novo coronary artery lesions. This study was published in Lancet (2016; 387:31-9. doi: 10.1016/S0140-6736(15)00447-X). 

View Dr. Garcia-Garcia’s publications on PubMed.


  • Research Areas
  • Cardiovascular