William Weintraub
William Weintraub

William S. Weintraub

Director of Population Health Research
MedStar Health Research Institute

Director of Heart Rhythm Research, Cardiac Electrophysiology
MedStar Heart & Vascular Institute

Professor of Medicine, Georgetown University

Dr. William S. Weintraub serves as the director of population health research for the MedStar Health Research Institute where he examines health outcomes within specific patient populations. Most recently, he served as primary investigator and chair of the presentation and publication committee of the CDC-sponsored Community Research Partnership, a MedStar Health surveillance study on COVID-19 community transmission and exposure.

In addition, Dr. Weintraub is a professor of medicine at Georgetown University. Previously he was Professor of Medicine at Jefferson University in Philadelphia and the John H. Ammon Chair in Cardiology and director of the cardiology section at Christiana Health Care System in Newark, Delaware. Dr. Weintraub also holds appointments as adjunct professor of health sciences at the University of Delaware and professor of medicine emeritus and professor of public health emeritus at Emory University School of Medicine.

Dr. Weintraub received his MD degree from Johns Hopkins in 1975. After training at Boston University, Mount Sinai Hospital in New York, and the University of Pennsylvania in Philadelphia, he was appointed to the University of Pennsylvania faculty in 1980. He was recruited to Emory University in 1986 to direct efforts in outcomes research in cardiovascular medicine, overseeing the Emory cardiovascular databank. He founded the Emory Center for Outcomes Research (ECOR) in the mid-1990's, publishing over 200 papers while on the faculty at Emory.

While at Emory, Dr. Weintraub was appointed the first chairman of the National Cardiovascular Data Registry of the American College of Cardiology. Dr. Weintraub served as chairman of the steering committee for the ACC NCDR Cath-PCI registry as well as on the ACC NCDR management board. Dr. Weintraub has served on multiple committees for the ACC and the American Heart Association. He has served as the President of the Great Rivers Affiliate of the ACC, and has won multiple awards from the ACC and AHA, including becoming as Master of the American College of Cardiology and Science Advocate of the Year from the American Heart Association.

In addition to working on registries, Dr. Weintraub has been working on clinical trials since the 1980's. He was a principal investigator on EAST, LRT, RESTORE, TACTICS-TIMI 18, SoS, EPHESUS, CURE, CREDO and COURAGE. Activities in all of these trials have involved multicenter collaborations. The activities on both registries and clinical trials have afforded Dr. Weintraub extensive experience both leading multi-institutional research activities and participating in the leadership group.

Dr. Weintraub has specialized knowledge and skill in health status assessment and health care economics. He has been involved in the economic analysis for each of the trials noted above, and in the quality of life analysis for TACTICS-TIMI 18, SoS, EPHESUS, COURAGE and REDUCE-IT. Dr. Weintraub was one of the first in cardiovascular medicine to develop an economic analysis alongside a clinical trial. Dr. Weintraub remains active in this endeavor.

Dr. Weintraub has also been involved in informatics for over 25 years since his development of the cardiovascular database at Presbyterian-University of Pennsylvania Medical Center and remains on the Informatics Committee of the American College of Cardiology. Dr. Weintraub oversees the extensive informatics development in cardiovascular medicine at Christiana, working with information services at Christiana. Information services and the Christiana outcomes center work in a deeply collaborative relationship to bring cutting edge technology as well as access to data from complex databases to bear on outcomes projects.

Dr. Weintraub has been heavily involved in committee activity for the American Heart Association and the American College of Cardiology. In addition to the database committees noted above, he has been on the steering committee for the interdisciplinary working group on Quality of Care and Outcomes Research since the IDWG was founded. He has been on the program committees for the American Heart Association Scientific Sessions, the American College of Cardiology, and the American Heart Association Forum on Quality of Care and Outcomes Research. He has been on the Research Committee of the American Heart Association, the American College of Cardiology Informatics Committee, and the American College of Cardiology Data Standards Committee. Dr. Weintraub has also served on the board of trustees of the American College of Cardiology.

Research Interests

Dr. Weintraub's research interests include

  • Population health research
  • Epidemiology
  • Health care economics
  • Health status assessment

Selected Research

Hypertrophic Cardiomyopathy (HCM) Registry

Dr. Weintraub currently serves as the director of the Clinical and Data Coordinating Center for the NHLBI-sponsored Hypertrophic Cardiomyopathy Registry, which seeks to improve risk prediction in hypertrophic cardiomyopathy by incorporating cardiovascular magnetic resonance, genetic, and biomarker data. 

Improving outcomes in treating lower systolic blood pressure target

Dr. Weintraub serves as the principal investigator of the NHLBI sponsored Optimize SPRINT study, based on the SPRINT trial of intensive treatment of hypertension.

Multiple industrial sponsored investigations of cost-effectiveness of therapy

View Dr. Weintraub's publications on PubMed

Research Areas

  • Health Services/Quality/Outcomes
    Health Economics, Systems, and Policy
    Population Health