Syed Mohammed Karim, MD| Orthopedic Surgery, Orthopedic Oncology | MedStar Health
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Syed Mohammed Karim

Syed Mohammed Karim, MD
Provider is directly employed by MedStar Health

4.8 out of 5 (119 reviews)

Specialties: Orthopedic Surgery, Orthopedic Oncology

Languages: English, Hindi, Urdu

About me

S. Mohammed Karim, MD is a board-certified orthopaedic surgeon who is dual fellowship trained in spine surgery and orthopaedic oncology—one of only a handful of surgeons nationwide with such training and experience. At MedStar Health, he specializes in the surgical treatment of patients with bone and soft tissue tumors / cancers. He sees patients at MedStar Franklin Square Medical Center and MedStar Union Memorial Hospital.

As a comprehensive musculoskeletal and spinal oncology surgeon, Dr. Karim enjoys helping those with both primary tumors (such as sarcomas) and metastatic tumors throughout the entire body including the spine, sacrum, pelvis, and extremities. He performs surgery for tumors causing spinal cord compression; spinal fractures/instability from tumors; pathologic or impending fractures in the arms, legs, and pelvis; and malignant bone and soft tissue tumors in all parts of the body. Dr. Karim believes firmly that cancer care is a “team sport” and works closely with medical oncologists, radiation oncologists, pathologists, radiologists, plastic surgeons, and other surgical subspecialists of MedStar Health to provide the best treatment possible to each patient. In addition to cancer patients, he surgically treats those with degenerative spine conditions (such as spinal stenosis, spondylolisthesis, cervical myelopathy, and bulging discs), spinal trauma, spinal cord injuries, and spinal infections.

In addition to caring for patients, Dr. Karim conducts clinical research to improve the outcomes of patients with musculoskeletal and spinal tumors. His research has been published in peer-reviewed journals and presented at international conferences. Dr. Karim is a member of the AOSpine Knowledge Forum Tumor – an international group of surgeons and other cancer specialists who perform research to improve the care of patients with spinal tumors. He is also a member of the American Academy of Orthopaedic Surgeons and the North American Spine Society, for which he holds Committee Appointments in Spine Oncology, Robotics and Enabling Technology, and Resident and Fellow Education. He has a keen interest in education and enjoys teaching and mentoring medical students, residents, and fellows both in and out of the operating room. Beyond his medical career, Dr. Karim is a proud member of the Civil Air Patrol.

Clinical areas of focus

  • Benign Bone Tumor
  • Bone Cancer
  • Bone Cancer Surgery
  • Bone Cyst
  • Bone Lesions
  • Bone Metastasis
  • Bone Metastasis Treatment
  • Bone Sarcoma
  • Bone Sarcoma Surgery
  • Bone Tumor
  • Metastatic Bone Disease
  • Metastatic Bone Disease Treatment
  • Multiple Myeloma
  • Pathological Fracture
  • Resection Of Soft Tissue Tumor
  • Soft Tissue Sarcoma
  • Soft Tissue Sarcoma Surgery
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Conditions and procedures

Conditions I treat

  • Angiosarcoma
  • Benign Bone Tumor
  • Bladder Carcinoma
  • Bone Cancer
  • Bone Cyst
  • Bone Density Disorder
  • Bone Discontinuity
  • Bone Lesions
  • Bone Metastasis
  • Bone Sarcoma
  • Bone Tumor
  • Brown Tumor
  • Cervical Spine Tumor
  • Chordoma
  • Femur Shaft Fracture
  • Fibrosarcoma
  • Hand Tremor
  • Lipoma
  • Liposarcoma
  • Lumbar Spine Tumor
  • Malignant Neoplasm Of Connective And Soft Tissue
  • Metastatic Bone Disease
  • Multiple Myeloma
  • Neoplasm Of Uncertain Behavior
  • Nerve Tumors
  • Pathological Fracture
  • Pelvic Tumor
  • Sarcomas Of Skin And Soft Tissue
  • Skull Base Tumor
  • Soft Tissue Sarcoma
  • Spinal Metastases
  • Spine Tumor
  • Thigh Fracture
  • Thoracic Spine Tumor
  • Wrist And Hand Tumors
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Procedures I perform

  • Amputation Revision
  • Bone Biopsy
  • Bone Cancer Surgery
  • Bone Graft
  • Bone Metastasis Treatment
  • Bone Sarcoma Surgery
  • Ewing's Sarcoma Treatment
  • Femur Excision
  • Femur Fracture Stabilization
  • Flap Surgery
  • Forequarter Amputation
  • Ganglion Cyst Excision
  • Hindquarter Amputation
  • Hip Distraction
  • Hip Replacement For Metastatic Bone Disease
  • Knee Amputation
  • Metastatic Bone Disease Treatment
  • Pelvic Tumor Resection
  • Proximal Humerus Replacement
  • Reconstruction For Bone Defects
  • Resection Of Soft Tissue Tumor
  • Salvage Surgery
  • Soft Tissue Sarcoma Surgery
  • Spinal Spondylolysis Treatment
  • Toe Amputation
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Practice locations

Distance from Change LocationEnter your Location

3333 N Calvert St
Ste 655
Baltimore, MD, 21218

410-554-2715

Fax 443-656-9320

Get Directions

miles away

Fax 443-656-9320

9101 Franklin Square Dr
Ste 200
Baltimore, MD, 21237

410-554-2715

Fax 443-656-9320

Get Directions

miles away

Fax 443-656-9320

2118 Greenspring Dr
Ste 110
Timonium, MD, 21093

410-554-2715

Fax 443-656-9320

Get Directions

miles away

Fax 443-656-9320

Insurance

MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.

  • List of insurance plans we accept
    • IH-Indemnity
    • CareFirst Blue Preferred PPO
    • Magellan Complete Care of VA - VA Medicaid MCO
    • CareFirst FEP Blue Focus
    • Kaiser Permaenete Signature - Added Choice Cardiac Global
    • Anthem BCBS of VA HealthKeepers Plus
    • MD IPA (HMO) & MD IPA Preferred Cardiac Global
    • CareFirst BlueCross BlueShield Advantage Core/Enhanced
    • OCI Direct (HMO)
    • CareFirst Administrators
    • TriWest Healthcare Alliance
    • AMERIVANTAGE/Amerigroup Community Care
    • Medicare Direct
    • IH-Open POS Plus
    • Great-West Healthcare POS/CIGNA
    • United Healthcare Select HMO - EPO/NPP
    • AmeriHealth Caritas DC Healthy Families
    • Private Health Care Systems (PPO)
    • Coventry Health Care National Network PPO
    • Mamsi Life & Health (Indem./PPO)
    • Medicare FFS
    • CIGNA SureFit (HMO)
    • NYC Medicare Advantage Plus
    • Kaiser Permanente Medicare Plus
    • United Healthcare Choice
    • Optima Family Care MCO - VA Medicaid MCO
    • IH-Open Network Only Plus
    • CIGNA HMO Open Access
    • Optimum Choice
    • UHC Passport
    • Kaiser Permanente Medicare Advantage Signature and Select
    • Lasso Healthcare - Medicare Medical Savings Account
    • Geisinger Medicare Advantage
    • Tricare Reserve Select
    • WellPoint Maryland - Maryland Health Choice
    • IH-HMO
    • Coventry of Delaware HMO/PPO
    • Advantra Platinum (PPO)
    • Priority Partners - Maryland Health Choice
    • Aetna Student Health Insurance
    • CareFirst Federal Employee Program (Std. & Basic PPO)
    • Aetna Advantage 6350PD
    • Choice Fund PPO
    • Kaiser Permanente Select Cardiac Global
    • Johns Hopkins Advantage MD PPO
    • Aetna Better Health of MD
    • POS OA
    • Aetna Advantage 5750
    • UnitedHealthcare Medicare Advantage DSNP District of Columbia
    • Aetna Elect Choice/ Open Access (POS)
    • Private Fee-for-Service Plans (PFFS)
    • Mamsi Life & Health (Indem./PPO) Cardiac Global
    • UnitedHealthcare Individual Exchange Plans
    • United Healthcare Choice Cardiac Global
    • CIGNA EPO
    • Aetna Medicare Advantage HMO & PPO Plans
    • Aetna Traditional Choice (PPO)
    • Health Services for Children with Special Needs
    • TRICARE for Life East
    • Fee-for-Service (FFS) District of Columbia, Maryland and Virginia Medicaid
    • CIGNA PPO
    • TRICARE East Select
    • Police and Fire Clinic
    • Amerigroup DC Alliance
    • Aetna VA Exchange
    • CareFirst Blue Choice Opt Out Plus Open Access (POS)
    • MedStar Family Choice - Maryland Health Choice
    • United Healthcare Navigate Cardiac Global
    • IH-POS Plus
    • Anthem BCBS of VA Key Care POS/PPO/Indemnity
    • Aetna Signature Administrator PPO/TPA
    • IH-Network Only Plus
    • Aetna Managed Choice (POS)
    • Aetna Better Health of VA
    • Aetna Worker's Compensation Network
    • CareFirst MedStar Select PPO
    • Johns Hopkins Advantage MD PLUS PPO
    • DC/MD SHOP QHP Small Business Plans
    • United Healthcare Select Plus (POS)
    • CareFirst Blue Card Program
    • Jai Medical Systems - Maryland Health Choice
    • Kaiser Permanente Signature
    • United Healthcare Choice Plus Cardiac Global
    • Aetna Classic 5000
    • OA Plus
    • First Health PPO
    • Anthem BCBS Medi Blue Dual Adv
    • HealthyBlue PPO
    • UnitedHealthcare Medicare Adv. Special Needs Plans
    • BlueChoice Open Access
    • United Medicare Private Fee-for-Service (PFFS) plans
    • Alterwood Advanatge HMO & DSNP Plans
    • Aetna Quality Point of Service (POS)
    • Kaiser Permanente Flexible Choice 3-tier POS
    • M.D. IPA Preferred (POS)
    • Kaiser Permanente Signature - Added Choice
    • Uniformed Services Family Health Plan
    • MedStar Family Choice DC Healthcare Alliance
    • Blue Choice Advantage
    • CIGNA Indemnity
    • United Healthcare Choice Plus
    • UnitedHealthcare and AARP Medicare Complete Plans
    • Anthem BCBS Medi Blue Plus
    • UHC Group Medicare Advantage Plans (HMO, POS, PPO)
    • Options PPO Cardiac Global
    • MultiPlan, Inc
    • Erickson Advantage Plans
    • CareFirst Blue Choice Opt Out Open Access
    • CIGNA HMO & Network (HMO)
    • Aetna HMO-Open Access/Select OA/HealthFund/Health Network Option OA
    • CareFirst Community Health Plan of MD
    • Humana Medicare Advantage - HMO Open Access
    • Veterans Affairs Community Care Network
    • United Student Resources
    • CareFirst Maryland Point of Service Plan
    • Anthem Federal Employee Program Basic
    • CIGNA Connect EPO
    • Humana Medicare Advantage - PPO
    • Aetna Open Choice (PPO)
    • Anthem BCBS of VA HealthKeepers (HMO)
    • Choice Care Network/HUMANA (PPO)
    • Cigna True Choice Medicare (PPO)
    • IH-PPO
    • Anthem BCBS Medi Blue SNP
    • CIGNA POS/Network POS
    • Select HMO/HealthFund/Health Network
    • CareFirst Dual Prime HMO-SNP
    • Cigna True Choice Plus Medicare (PPO)
    • Aetna Medicare Advantage PFFS Plan
    • CareFirst Group Medicare Advantage
    • Cigna TotalCare (HMO D-SNP)
    • United Healthcare Select HMO-EPO/NPP Cardiac Global
    • Aetna Advantage 6350
    • IH-Open POS II
    • BCBS Out-of-State Medicare Plans (Blue Advantage)
    • Healthy Blue (HMO, POS)
    • CIGNA PPO Plus
    • Kaiser Permanente Flexible Choice POS Cardiac Global
    • CareFirst Group Medicare Advantage prescription drug benefit (PPO)
    • Johns Hopkins Advantage MD HMO
    • Choice POS II Open Access
    • Aetna Managed Choice Open Access (POS)
    • Choice POS
    • HUMANA/Choice Care Medicare Plans (Choice, Gold Choice)
    • United Healthcare Options (PPO)
    • IH-EPO Plus
    • Optimum Choice & Optimum Choice Preferred (POS) Cardiac Global
    • M.D. IPA (HMO)
    • Aetna Basic
    • Aetna Classic 3500
    • AmeriHealth Caritas DC Healthcare Alliance
    • Maryland Physicians Care MCO
    • Choice POS II
    • Cigna Alliance Medicare (HMO)
    • Kaiser Permanente Select - Added Choice
    • Sentara Health
    • Optimum Choice Preferred (POS)
    • HighMark
    • Aetna Premier 200PD
    • IH-POS
    • Core Essential (HMO)
    • Amerigroup DC Healthy Families
    • United Healthcare Community Plan - VA Medicaid MCO
    • CareFirst MedStar PPO
    • CareFirst (NCA) Indemnity
    • Anthem Federal Employee Program Standard
    • Employee Health Plan
    • MedStar Family Choice DC Healthy Families
    • BCBS of Michigan (BCN Advantage,Security Blue, Freedom, Medicare PLUS Blue Group PPO)
    • IH-Open EPO Plus
    • Medicare Advantage - Advantra Value (PPO)
    • CareFirst EPO
    • CareFirst NASCO
    • Kaiser Permanente HMO Plus and DHMO Plus Member
    • Beech Street PPO
    • Kaiser Permanente Select
    • Aetna Classic 5000PD
    • Aetna HMO
    • Aetna Elect Choice/ EPO (Aetna Health Fund)
    • IH-Open HMO
    • Cigna Preferred Medicare (HMO)
    • Network OA
    • United HealthCare Community Plan - Maryland Health Choice Program
    • TRICARE East Prime
    • Anthem BCBS of VA HealthKeepers (POS & POS OA)
    • HumanaChoice Honor's plan PPO
    • Humana Gold Plus HMO
    • Kaiser Maryland Medicaid MCO
    • CareFirst Maryland Indemnity or PPO
    • IH-Open HMO Option
    • HumanaChoice PPO
    • Navigate
    • Cigna Achieve Medicare (HMO C-SNP)
    • Coventry Health Care of Virginia
    • First Health PPO
    • CareFirst BlueChoice HMO

Videos

Education

Board Certification: American Board of Orthopedic Surgery, Orthopedic Surgery

Fellowship: Mayo Clinic College of Medicine & Science (2021)

Fellowship: University of British Columbia GME (2020)

Residency: Massachusetts General Hospital (2019)

Medical School: Harvard Medical School (2014)

Awards

  • Baltimore Magazine, Top Doc, 2025

Ratings and reviews

  • Explanations the care provider gave you about your problem or condition

    4.9
  • Extent to which the care provider listened to you

    4.8
  • Care provider’s discussion of any proposed treatment (options, risks, benefits, etc.)

    4.9
  • Provider included you in decisions

    4.9
  • Concern the care provider showed for your questions or worries

    4.9
  • Likelihood of recommending this care provider to others

    4.9
  • Apr 30, 2026

    Dr Karim was all that you wanted - outstanding knowledge and bedside manner

  • Apr 27, 2026

    Good

  • Apr 4, 2026

    The doctor explained everything I needed to hear. I was so relieved when I left there.